Results 91 to 100 of about 1,356,854 (269)
The dataset in this article presents indigenous knowledge of Dayak, Malay, and Chinese ethnic communities in Sintang Regency, West Kalimantan, Indonesia.
Adriana Gandasari +8 more
doaj +1 more source
The baryon content of the local intergalactic medium
We describe our surveys of low column density Lyman-alpha absorbers [N(HI) = 10^(12.5-16.0) cm^-2], which show that the warm photoionized IGM contains 30% of all baryons at z < 0.1. This fraction is consistent with cosmological simulations, which also predict that an additional 20-40% of the baryons reside in hotter 10^(5-7) K gas, the warm-hot IGM (
Stocke, John T. +2 more
openaire +2 more sources
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Pragmatic Content in Global and Local ELT Textbooks
This study is an attempt to explore the frequency of pragmatic content occurrence represented as three speech acts of requesting, refusing, and apologizing in global and local English Language Teaching (ELT) textbooks.
Hussein Meihami, Mobin Khanlarzadeh
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
This study aims to explain the Local Content Curriculum of Arabic-Malay Script in Improving Literacy Through Local Wisdom at the Nurul Iman Seberang Islamic School in Jambi City.
Eva Iryani +4 more
doaj +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source

