Results 51 to 60 of about 1,537,044 (314)

Local fat content determines global and local stiffness in livers with simple steatosis

open access: yesFASEB BioAdvances, 2023
Fat accumulation during liver steatosis precedes inflammation and fibrosis in fatty liver diseases, and is associated with disease progression. Despite a large body of evidence that liver mechanics play a major role in liver disease progression, the ...
David Li   +2 more
doaj   +1 more source

Local Content

open access: yes, 2016
Local content refers to materials and products made in a country as opposed those that are imported. There is an increasing interest in the concept of local content as a means of supporting local economies and providing jobs (Belderbos & Sleuwaegen, 1997; Qiu & Tao, 2001; Corkin, 2012; Warner, 2011; Stephenson, 2013).  Local content is also seen a way
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Local Queuing Under Contention.

open access: yes, 2018
We study stability of local packet scheduling policies in a distributed system of n nodes. The local policies at nodes may only access their local queues, and have no other feedback from the underlying distributed system. The packets arrive at queues according to arrival patterns controlled by an adversary restricted only by injection rate rho and ...
Pawel Garncarek   +2 more
openaire   +3 more sources

RENSHAW ELEMENTS: LOCALIZATION AND ACETYLCHOLINESTERASE CONTENT [PDF]

open access: yesJournal of Histochemistry & Cytochemistry, 1968
Fine microelectrodes filled with molar potassium acetate solution and saturated with fast green FCF dye have been used to record from and localize Renshaw elements in L 7 of the cat spinal cord.
S D, Erulkar   +3 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Local involvement in harnessing crude oil and natural gas in Nigeria [PDF]

open access: yes, 2006
Vast financial investments have been made in the upstream crude-oil and natural-gas (CONG) sector in Nigeria, but have not resulted in significant benefits for most Nigerians. The associated major activities, e.g., exploration, drilling, production, well
Probert, Sydney D.   +3 more
core   +1 more source

Delivering public services through social media in European local governments [PDF]

open access: yes, 2020
Social media adoption by public administrations is usually related to the promotion of transparency, participation and collaboration. However, less attention has been paid to the utilisation of social media for public service delivery.
Villodre de Costa, Julián   +1 more
core   +1 more source

A Review of Job Role Localization in the Oil and Gas Industry

open access: yesEnergies, 2018
Job role localization is a strategic local content solution used by countries bearing natural resource stocks to maximize the long-term benefits of exploring and producing them. Currently, there is significant variation in how countries and organizations
Jack Pegram   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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