Results 41 to 50 of about 566,904 (264)
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Council Appointed Mayors in Spain: Effects on Local Democracy
Revista de Estudios de la Administración Local y Autonómica, 2017 This paper deals with the influence of having council appointed mayors on local governments. Five elements of local government systems are considered: the electoral system and its influence on the political composition of the local government; the local ...
María Jesús García García
doaj +3 more sources
Applied SciencesConsumer-accessible and user-friendly smart products such as unmanned aerial vehicles (UAVs), or drones, have become widely used, adaptable, and acceptable devices to observe, assess, measure, and explore urban and natural environments.
Christine Steinmetz-Weiss +3 more
doaj +1 more source
International Indigenous Policy Journal, 2017 This study explored the Walhallow Aboriginal community’s experiences with drinking water to gain a shared understanding about community concerns and to develop ways to address these concerns together. There is a strong connection between people and water,
Fidelis Jaravani +7 more
doaj +1 more source
Politeja, 2020 The Condition of Local Democracy in Poland in Light of the Council of Europe’s Standards and the European Charter of Local Self-Government Compliance Monitoring Mechanism. A Political Dimension In the article, I will discuss a model and a mechanism of
Mirosław Natanek
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
CECCAR Business ReviewLocal councils represent local public administration authorities with a major role, including in the field of local public services. Entities under the authority of local councils, although often legally organized in the form of commercial companies, are
Bogdan Cosmin GOMOI
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Understanding Local Government Cybersecurity Policy: A Concept Map and Framework
InformationCybersecurity is a crucial concern for local governments as they serve as the primary interface between public and government services, managing sensitive data and critical infrastructure.
Sk Tahsin Hossain +3 more
doaj +1 more source