Results 31 to 40 of about 6,008,404 (302)
Revue d'Études AutochtonesDepuis plusieurs décennies, les membres du peuple Walbunja (nation Yuin) aspirent à exercer leur souveraineté et affermir leur influence sur les projets de développement économique et de gestion environnementale concernant leur territoires terrestres et ...
Annick Thomassin +6 more
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BJPsych OpenAims To compare the funding, courses and delivery modalities of parenting training delivered across London borough councils, metropolitan district councils, and county councils in England. Methods Freedom of Information requests were piloted on 5 local
Rosemary Gorringe +4 more
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Legal Challenges of Local Decentralization in Iran [PDF]
Faṣlnāmah-i Pizhūhish-i Huqūq-i ̒UmūmīIntroductionDecentralization has established itself globally as a preferred model of governance in today’s world. In this respect, the present article highlights the value of adopting a decentralized model of government that grants broad powers—not only ...
Salah Ghsemyani +3 more
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FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Commonwealth Journal of Local Governance, 2012 There is growing concern about climate change impacts on local government areas. In Australia, the federal carbon tax (from 1 July 2012) will also increase costs for local councils. This paper evaluates what carbon mitigation (i.e.
Heather Zeppel
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FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Competencias de los municipios vascos: tipología y régimen jurídico
Revista Vasca de Administración Pública, 2017 The Act on Local Institutions of Euskadi (2016) boasts several important novelties in relation with local competences. This system eventually shall be completed with specific legislation enacted by the Basque Parliament and with foral laws.
Francisco Velasco Caballero
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Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source