Results 141 to 150 of about 10,658,001 (305)
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Parution : nouveau numéro de la Santander Art & Culture Law Review
Un nouveau numéro de Santander Art & Culture Law Review - revue polonaise spécialisée dans le droit de la culture et le droit de l'art - est paru durant l'été 2018 (numéroté 2/2017-3).
Droit, patrimoine & culture
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The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Background/purpose. Education in the 21st century requires the cultivation of students' competencies in critical thinking, creativity, communication, and collaboration.
Handy Ferdiansyah +3 more
doaj +1 more source
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
Culture et gouvernance locale Culture and local governance
La revue « Culture et gouvernance locale » vous invite à soumettre un article pour son troisième volume. CGL est une revue académique bilingue qui accepte les articles en anglais et en français. Publiée par le Centre de gouvernement local de l’Université
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Local Art Festivals and Local Culture Tourism: Is Local Art ‘indigenized’ as local culture?
openaire +1 more source
In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller +3 more
wiley +1 more source

