Results 81 to 90 of about 11,285,176 (305)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Frente : Órgano de la Junta Local del Frente Sindicalista Revolucionario de Madrid: Año I Número 1 - 1968 julio

open access: yes, 1968
Copia digital. España : Ministerio de Cultura y Deporte.
Frente Sindicalista Revolucionario de Madrid. Junta Local
core   +2 more sources

Pembelajaran Lingkungan Berbasis Kearifan Lokal dengan Model Experiential Learning

open access: yesJurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2019
: Environmental damage that occurs on earth is caused by human activities. Human activities that use the environment excessively cause the environment to be damaged.
Bunga Dwi Immaniar   +2 more
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Kearifan Lokal Nusa Tenggara Timur sebagai Sumber Bahan Ajar Menulis Teks Eksplanasi untuk Siswa Kelas XI

open access: yesJurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2019
: The purpose of this development research is to produce explanatory text teaching materials based on local wisdom of East Nusa Tenggara for class XI students. Local wisdom-based teaching materials can be used as a source of learning.
Petronela Mau   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

CULTURAL RESILIENCE IN THE ERA OF GLOBALIZATION: MAINTAINING HERITAGE AND LOCAL WISDOM FOR FUTURE GENERATIONS [PDF]

open access: yes
Globalization has brought significant changes in various aspects of life, including culture. Technological developments and the rapid flow of information create intense cultural interactions, but also threaten the preservation of local culture.
Masyuri, Muhammad, Karomah, Lailatul
core   +1 more source

Menuju Pembangunan Partisipatif (bagaimana Mendayagunakan Kebudayaan Lokal)

open access: yesJKAP (Jurnal Kebijakan dan Administrasi Publik), 2015
Grassroot people are development actors who determine course of development so that it will bring about a more valuable change. That is the basic argument as why people autonomy and participation are the keywords for the development achievement. Research
Irwan Abdullah
doaj   +1 more source

Agama, Etnisitas dan Perdamaian di Pulau Enggano Provinsi Bengkulu

open access: yesHanifiya, 2020
This article explores the diversity of ethnicities and religions in the Engganese society, which has become color in their life dynamics—local wisdom based on customary rules succeeded in uniting differences into peace.
Intan Permata Sari
doaj   +1 more source

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