Results 91 to 100 of about 10,334,606 (306)
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
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CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
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Rethinking Culture and Cultural Analysis
The texts in this collection are revised versions of presentations given at the Coimbra International Conference on the Semantics of Culture emph Why ``Culture''?, held on November 24-25, 2011.
core +1 more source
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Since the late twentieth century, local culture has gained prominence in the Japanese society in several ways. Not only is local culture closely related to national and regional policies in terms of cultural properties faced with crisis but is also utilized in several realms such as agricultural politics, tourism, economic revitalization, and ...
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The history and publication of Ethnologia Fennica in the years 1971- 1986 are closely connected with the Seurasaari Foundation, founded in 1956 to support Seurasaari Open-Air Museum and ethnological research generally, and especia ly with Mr Niilo Valonen, who was Professor of Finno-Ugrian Ethnology at the University of Helsinki from 1961 to 1977.
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Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Research into local culture: Implications for participatory development
This paper examines the importance of culture and participation in development efforts. In this regard, it looks at the problems which have arisen as the result of those receiving aid, being regarded as objects rather than subjects with their own culture
Anacleti, Odhiambo
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This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source

