Results 231 to 240 of about 11,285,176 (305)

Modeling Early Metastatic Progression in Breast Cancer Using a Barrier‐Free, Perfusable Spheroid‐on‐a‐Chip Platform

Advanced Healthcare Materials, EarlyView.
Open‐port, barrier‐free microfluidic device for modeling early metastatic progression. A centrally positioned tumor spheroid releases invasive cells that migrate through the surrounding matrix and intravasate into endothelialized lateral channels.
Vira Sharko, Claudia Olaizola‐Rodrigo, Clara Bayona, Teodora Ranđelović, Rosa Monge, Estela Solanas, Sara Oliván, Ignacio Ochoa   +7 more
wiley   +1 more source

From Compliance to Strategic Partner: The Transformation of Regulatory Affairs in AstraZeneca Local Affiliates. [PDF]

Pharmaceut Med
Fernández Montero MC, de Munnik H, Sondej A, Pérez Domínguez A.   +3 more
europepmc   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

Bacterial profile and antimicrobial susceptibility patterns of blood culture isolates in pediatric patients at children hospital, Sukkur: a one-year retrospective analysis. [PDF]

Iran J Microbiol
Ahmed W, Bashir B, Naz S, Kashif M, Ali S, Bhanbhuro F, Unar F, Arijo S, Shabbir Z.   +8 more
europepmc   +1 more source

Bioprinted Stiffness‑Tunable Pancreatic Microniches to Decode Early Tumor Initiation Mechanisms

Advanced Healthcare Materials, EarlyView.
Stiffness‐tunable GelMA microniches generated by microvalve bioprinting preserve wild‐type acinar identity while revealing a nonlinear, Kras‐dependent response to matrix mechanics. Intermediate stiffness promotes acinar‐to‐ductal metaplasia and proliferation, defining a permissive mechanical window.
Aurelien Mazet, Charles Handschin, Theo Desigaux, Nathalie Dusserre, Marie‐Laure Stachowicz, Shane Fennell, Malou Lea, Silvia Arcucci, Benoît Thibault, Jean‐Christophe Fricain, Julie Guillermet‐Guibert, Hugo Oliveira   +11 more
wiley   +1 more source

How is practitioner-led quality and safety improvement sustained across a whole hospital? A process evaluation of a practice development programme. [PDF]

Front Health Serv
Peet J, Tuqiri K, Smoother R, Sheppard-Law S, Douglas C.   +4 more
europepmc   +1 more source

Biocompatible Conjugated Electrospinning Nanofibrous Membrane With Self‐Powered Piezoelectric Capacity for Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
A self‐powered PCL/gelatin‐PVDF‐TrFE/MXene conjugated electrospun membrane integrates biocompatibility with enhanced piezoelectric responsiveness. Mechanical deformation is converted into localized electrical signals that stimulate wound‐repair cells proliferation and migration, promote angiogenesis and tissue remodeling, and accelerate full‐thickness ...
Diandian Li, Ke Wu, Yangyang Lu, Qinglan Xia, Jialong Chen, Yifan Zhang, Zhaoyu Chen, Zhiyuan She, Junjin Jie, Juzi Xia, Muran Zhou, Aimei Zhong   +11 more
wiley   +1 more source

Microbiological Spectrum and Antimicrobial Susceptibility Patterns of Culture-Positive Thoracic and Respiratory Specimens in Syria: A Retrospective Laboratory-Based Study. [PDF]

Int J Microbiol
Aldakak MA, Senjab A, Aljbawi H, Alkhatib I, Alkhatib A, Darwish B.   +5 more
europepmc   +1 more source