Results 101 to 110 of about 10,658,001 (305)
STUDY OF IT ROLE IN STRENGTHENING LOCAL CULTURE
, 2011 -Arts as a part of culture is a product of human creativity as an expression of feel, sense, emotion, and perception. Arts also affected by environment.
Rijayana, Iwan, Falahah
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
The Practice and Inheriting of the Bai People’s local Culture of Dali [PDF]
, 2015 This paper discusses the status quo and problems of the local cultural heritage of ethnic minorities in the southwest China, which is in the context of modernization. The data in this paper are obtained through long-term field work.
LI, Xiufang
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Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Hedonic Pricing Evaluation on Agritourism Activity in Italy: Local Culture-based or Facility-based? [PDF]
This paper focused on how and what diversified activities influence the price level of agritourism. A hypothesis that contrasts two directions was examined: facility-based and local culture-based activities.
Ciani, Adriano, Ohe, Yasuo
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, 2009 En France, depuis le début des années 1990, des « affaires » médiatiques en nombre inédit révèlent une conflictualité croissante entre agents politiques locaux et professionnels de la culture, s’opposant notamment sur les formes et les finalités ...
Matz, Kevin
core +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Analysis of How the Local University Library to Service for the New Rural Culture Construction [PDF]
, 2015 The construction of socialist new countryside is a practical example of scientific socialism theory in China, and it is the performance of the Party Central Committee to implement the scientific concept of development.
ZENG, Ying
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