Results 61 to 70 of about 10,658,001 (305)

Guidelines on sustainable mobility : walkability and accessibility

, 2023
This is the third published guideline document, in a series of documents which are being published under the Resident First project headed by the Local Councils’ Association and endorsed by all Local Councils in Malta and Gozo.
Zammit, Antoine, Local Councils' Association   +1 more
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Exploration of Ethnomathematics in Banyumas Traditional Food in Sokaraja Area, Central Java

Edumatica: Jurnal Pendidikan Matematika
This study aims to explore the ethnomathematics concepts found in traditional Banyumas foods and their potential as mathematics teaching materials for junior high school students.
Annisa Fitri Wulandari, Arif Rahman Hakim, Soeparlan Kasyadi   +2 more
doaj   +3 more sources

Sickness Absence and Local Cultures [PDF]

, 2010
Sickness absence has been found to vary substantially across geographical areas. There are large differences between different countries but also between different regions within a particular country. In the literature some of these observed differentials have been suggested to stem from differences in local norms with regard to the legitimacy of ...
Ekblad, Kristin, Bokenblom, Mattias
openaire   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

The local culture as a means to explore the processes of social coexistence: A case study on a neigborhood in the city of Rome

Community Psychology in Global Perspective, 2015
Community-based interventions for urban sustainability need to develop a consistent theoretical framework dealing with the individual-context relationship by exploring community affective processes of sense-making, in order to overcome a nomothetic and ...
Andrea Caputo
doaj   +1 more source

Improving early childhood education students’ knowledge about culture as the local wisdom [PDF]

, 2020
Indonesia is a big country with many cultures; therefore, Indonesian children have to learn their local wisdom beginning with their early years. Young children are in their golden years, so they have to be helped to acquire all the knowledge they need ...
Titi Chandrawati, Chandrawati, Titi
core   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Desvelamento do limiar discursivo de uma marca global em uma cultura local

Cadernos EBAPE.BR
Com o advento da globalização inicia-se uma nova forma de convivência entre as sociedades, cuja possibilidade contribui para gerar um emaranhado campo de cruzamentos culturais e permite o estabelecimento de valores universais em meios locais.
Flávia Zimmerle da Nóbrega Costa, André Luiz Maranhão de Souza Leão   +1 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source