Results 111 to 120 of about 10,289,866 (260)

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Big Local Partnership Member Surveys, 2016-2024

open access: yes
copyright UK Data Service and data collection copyright owner.Big Local is a long-term, place-based funding programme in England aimed at empowering residents in selected communities to lead local change, build community capacity, and improve outcomes ...
Local Trust
core   +1 more source

Reflection of “O Nga: Laa” Value behind Capital Accounting Practices by Farmers

open access: yesAktiva
Purpose: This study aims to reveal capital accounting implemented by rice farmers based on local cultural values. Design/methodology/approach: This study uses an Islamic paradigm with an Islamic ethnomethodology approach.
Mohamad Anwar Thalib   +2 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Local Government Regional Management Plan - Northern Region

open access: yes, 2012
Made available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT).'The Plan is set out in five sections. Background provides an overview of legislative requirements of Regional Management Plans.
Local Government Support Unit
core  

Designing Local Culture-based Canva Narratives to Enhance Reading Skills for Junior High School Students

open access: yesJEELS (Journal of English Education and Linguistics Studies)
The study aimed to develop culturally relevant reading materials for eighth-grade students at one of the state junior schools in Ponorogo, Indonesia, using Canva as a digital platform.
Like Trisnawati Hardina   +2 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Embedding local cultural richness in English language education: a place-based dual-core approach for rural schools in China

open access: yesFrontiers in Education
This study examines the implementation of place-based education in rural English teaching in China through a mixed-methods approach, encompassing surveys and interviews with rural middle school students and teachers.
Hong Shi, Lirui Ma
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

ACCULTURATION OF ISLAMIC CULTURE AND LOCAL CULTURE IN DRUMING TRADITION IN PANJANG REGION VILLAGE, KUCHING, SARAWAK, MALAYSIA

open access: yesBatuthah
This article focuses on the acculturation of Islamic culture and local culture in the Bergendang tradition. The purpose of writing this article is to preserve the traditions that have been carried out by the Rantau Panjang Malay community in order to ...
Mohammad Shafiq Bin Asan
doaj   +1 more source

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