Results 101 to 110 of about 11,285,176 (305)

Local Culture and Community Through a Digital Lens: Viewpoint on Designing and Implementing a Virtual Second Look Event for Residency Applicants. [PDF]

JMIR Med Educ, 2023
Martindale JM, Carrasquillo RA, Otallah SI, Brooks AK, Denizard-Thompson N, Pharr E, Choate N, Sokolosky M, Strauss LD.   +8 more
europepmc   +1 more source

Theorizing Local Culture

Japanese Journal of Human Geography, 2005
Since the late twentieth century, local culture has gained prominence in the Japanese society in several ways. Not only is local culture closely related to national and regional policies in terms of cultural properties faced with crisis but is also utilized in several realms such as agricultural politics, tourism, economic revitalization, and ...
openaire   +3 more sources

Organisational culture and its influence on strategy in local media

, 2016
This paper is concerned with understanding organisational culture within local news media organisations. It explores the conflict faced by local news organisations between community values and commercial imperatives.
O'Hara, S.
core  

New Zealand culture of intoxication: Local and global influences [PDF]

, 2010
This article shows that attitudes towards and behaviours involving the consumption of alcohol in New Zealand have long been problematic. It provides an historical account of social, economic and legislative factors which have influenced the development ...
Brett Mcewan, Maxine Campbell, Swain, David, McEwan, Brett James, David Swain, Campbell, Maxine M.   +5 more
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Designing Culturally Responsive Education Strategies to Cultivate Young Children's Cultural Identities: A Case Study of the Development of a Preschool Local Culture Curriculum. [PDF]

Children (Basel), 2022
Shih YH.
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Study of nonsynchronous online teaching of regional anatomy for international students integrated with medical humanities and local culture during COVID-19 pandemic. [PDF]

Surg Radiol Anat, 2023
Hao Y, Ding H, Li Q, Lin M, Ibrahim A, Wang X, Wu Y, Leng S.   +7 more
europepmc   +1 more source

Cultures locales

Tandis que les « recherches actuelles en sciences sociales théorisent souvent la culture comme des “représentations collectives” – des vocabulaires, des symboles ou des codes – qui structurent les capacités des gens à réfléchir et à agir », Nina Eliasoph et Paul Lichterman se sont intéressés à la façon dont les groupes mettent en œuvre des formes ...
openaire   +2 more sources

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source