Results 91 to 100 of about 10,658,001 (305)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
BuildingsThe purpose of this paper is to introduce the perspective of the “socio-spatial” relationship, to construct a theoretical analysis framework for the reconstruction of rural cultural space, and to explore effective strategies for the reconstruction of ...
Senyu Lou +3 more
doaj +1 more source
New Zealand culture of intoxication: Local and global influences [PDF]
, 2010 This article shows that attitudes towards and behaviours involving the consumption of alcohol in New Zealand have long been problematic. It provides an historical account of social, economic and legislative factors which have influenced the development ...
Brett Mcewan +5 more
core +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Japanese Journal of Human Geography, 2005 Since the late twentieth century, local culture has gained prominence in the Japanese society in several ways. Not only is local culture closely related to national and regional policies in terms of cultural properties faced with crisis but is also utilized in several realms such as agricultural politics, tourism, economic revitalization, and ...
openaire +3 more sources
Returning culture to peacebuilding : contesting the liberal peace in Sierra Leone [PDF]
, 2010 This thesis investigates the advantages and limitations of applying culture to the analysis of violent conflict and peacebuilding, with a particular focus on liberal peacebuilding in Sierra Leone.
Viktorova Milne, Jevgenia
core +2 more sources
CULTURAL RESILIENCE IN THE ERA OF GLOBALIZATION: MAINTAINING HERITAGE AND LOCAL WISDOM FOR FUTURE GENERATIONS [PDF]
Globalization has brought significant changes in various aspects of life, including culture. Technological developments and the rapid flow of information create intense cultural interactions, but also threaten the preservation of local culture.
Masyuri, Muhammad, Karomah, Lailatul
core
Creative small settlements. Culture-based solutions for local sustainable development. [PDF]
, 2017 Culture can play a fundamental role in fostering sustainable patterns of urban and regional development. This is the message of the Global Report ‘Culture for Sustainable Urban Development’, which UNESCO has coordinated for the UN-HABITAT III Conference (
Verdini, G., Ceccarelli, P.
core
Ethnologia Fennica. Finnish Studies in Ethnology, 2013 The history and publication of Ethnologia Fennica in the years 1971- 1986 are closely connected with the Seurasaari Foundation, founded in 1956 to support Seurasaari Open-Air Museum and ethnological research generally, and especia ly with Mr Niilo Valonen, who was Professor of Finno-Ugrian Ethnology at the University of Helsinki from 1961 to 1977.
openaire +2 more sources
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source