Results 171 to 180 of about 411,066 (258)

A stepwise antimicrobial and diagnostic stewardship intervention for ordering urine cultures in Saudi Arabia: a quasi-experimental study. [PDF]

Front Cell Infect Microbiol
Alghamdi A, Khan MA, Alraey M, Alaboud M, Farooqi I, Allam A, Alghamdi L, Alissa A, Bahdailah A, Joseph M, Almangour TA, Aleissa MM.   +11 more
europepmc   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Quality improvement: enhancing antibiotic stewardship for suspected early onset neonatal infection by refining use of the Kaiser Permanente screening tool and using a CRP threshold of 20 mg/L. [PDF]

BMJ Paediatr Open
Brown KN, Davidson S, Craig R, Mitchell A, Falconer O, Johnson MJ.   +5 more
europepmc   +1 more source

A Data Driven Review of In Vitro Electrical and Mechanical Stimulation for Post‐Acute Phase Wound Healing

Advanced Healthcare Materials, EarlyView.
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess, Ellen F. Marsh, Veronica M. Lucian, Malavika Nair   +3 more
wiley   +1 more source

Sex-based considerations in the choice for a TLR9 or TLR7/8 agonist to arm the sentinel lymph node in early-stage melanoma. [PDF]

Oncoimmunology
Notohardjo JCL, Toffoli EC, Muijlwijk T, van den Hout MFCM, Kandiah V, Labots M, van de Ven R, van den Eertwegh AJM, de Gruijl TD.   +8 more
europepmc   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Risk Factors for Discordance Between Synovial Fluid Culture and Intraoperative Cultures in Revision Arthroplasties: Results From a European Multicentre Observational Study. [PDF]

JB JS Open Access
Ottink KD, Olearo F, Vaznaisiene D, Rolvien T, Kaoual S, Morreel E, Bîrluţiu V, Gómez-Junyent J, Lindberg-Larsen M, Reissier S, Rossi N, Dolores Del Toro Lopez M, Widerström M, Fernandez Sampedro M, Veltman ES, Petersdorf S, Rohde H, Wouthuyzen-Bakker M.   +17 more
europepmc   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Performance and Cost-Efficiency of an MPT64 Assay for Detecting <i>Mycobacterium tuberculosis</i> Complex in a Setting With Frequent Nontuberculous Mycobacteria Isolation. [PDF]

J Korean Med Sci
Yu HJ, Kim JA, Song HM, Lee KA, Kim H, Yoo IY, Kim TY, Huh HJ.   +7 more
europepmc   +1 more source

3D‐Printed Piezoionic/Bioelectronic Hydrogel for Electro‐Metabolic Regulation of Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
A 3D‐printed piezoionic GPMx hydrogel enables stable electromechanical signal generation under mechanical loading, exhibiting long‐term durability and low fatigue. As a bioactive patch, it restores endogenous bioelectricity to stimulate osteogenesis via Ca2+ influx and mitochondrial activation, while simultaneously enabling label‐free alkaline ...
Sayan Deb Dutta, Myoung Joon Jeon, Youjin Seol, Ki‐Taek Lim   +3 more
wiley   +1 more source