Results 61 to 70 of about 1,701,832 (305)

Universalitas Islam dan Lokalitas Budaya dalam Bingkai Islam Nusantara

Teosofi: Jurnal Tasawuf dan Pemikiran Islam, 2018
Islam has both universal and particular dimension, where the universality of Islam is reflected in the maqāṣid al-sharī‘ah, i.e. public benefits, whereas the Islamic particularity deals with practical aspects of the Islamic law in the human life ...
Ishom Fuadi Fikri
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Religion, politique et culture (s), quelle problématique de la Nation ?

إنسانيات, 2010
It’s a question of taking some intuitions, hypotheses and empirical facts into account, concerning the statute of religion and more exactly Islam, in a non urban Algerian society, namely before1954, intuitions arising from on the field contact between ...
Fanny Colonna
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Local Cultures of Advice Tie Formation

Journal of Organizational Sociology
Informal social networks and especially advice networks are a key subject of organizational sociological research. The formation of these networks has so far been explained on the basis of universal tie-formation mechanisms.
Roth Philip, Scheidgen Katharina
doaj   +1 more source

Cultures of caste and rural development in the social network of a south Indian village [PDF]

, 2015
Cultures of caste in much of rural India have become entangled with institutions of rural development. In community-driven development, emphasis on “local resource persons” and “community spokespersons” has created new opportunities for brokerage and ...
Baviskar A., Bokil M., Dumont L., Fuller C. J., Gupta D., Johnson C., Karamsi S. R., Latour B., Mines D. P., Mische A., Moffat M., Mosse D., Mosse D., Natarajan B., Prasad S., Simmel G., Spillman L., Still C., Swaminathan P.   +18 more
core   +4 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Situations, Networks and Culture—The Case of a Golden Wedding as an Example for the Production of Local Cultures

Forum: Qualitative Social Research, 2012
The article focuses on the way events are connected with preceding events of the same type carrying out a participatory observation on a golden wedding celebrated in a small village in the middle of Germany.
Christian Stegbauer
doaj  

Shin, Cin, and Jinn in far east Asian, central east Asian, and middle eastern cultures : case studies in transethnic communication by exchange of terminology for elementary spiritual concepts of ethic groups [PDF]

, 2008
Methodology and Objects: Methodologically, from a diachronic linguistics perspective regarding the concept of the shin, spirits in folk belief in China and neighbouring cultures, we compare texts that comprise meanings a) historically in the local ...
Haase, Fee-Alexandra
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source