Results 81 to 90 of about 9,654,838 (253)

Guidelines on sustainable mobility : walkability and accessibility

open access: yes, 2023
This is the third published guideline document, in a series of documents which are being published under the Resident First project headed by the Local Councils’ Association and endorsed by all Local Councils in Malta and Gozo.
Zammit, Antoine   +1 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Asymptotic Theory for Zero Energy Density Estimation with Nonparametric Regression Applications [PDF]

open access: yes
A local limit theorem is given for the sample mean of a zero energy function of a nonstationary time series involving twin numerical sequences that pass to infinity.
Peter C. B. Phillips, Qiying Wang
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

On the stability and structure relaxation of metallic nanocages

open access: yesФизико-химические аспекты изучения кластеров, наноструктур и наноматериалов
The problem of the thermal stability of mono- and binary metallic nanocages consisting of gold and silver atoms with the same nuclearity of 3000 atoms is considered.
D.N. Sokolov   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Local vibrational density of states in disordered graphene

open access: yesSemiconductor Physics, Quantum Electronics & Optoelectronics, 2016
Local vibrational density of states for disordered graphene has been calculated via Green’s functions method. Disordered material has been modeled with Bethe lattice. Density of states does not include particularities specific for ideal graphene.
D.L. Kardashev
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Density peak clustering algorithm based on weighted mutual K-nearest neighbors

open access: yesFrontiers in Applied Mathematics and Statistics
Ever since Density Peak Clustering (DPC) was published in Science, it has been widely favored and applied in various fields due to its concise and efficient computational theory. However, DPC has two major flaws. On the one hand, it fails to find cluster
Chunhua Ren   +4 more
doaj   +1 more source

Limits on the local dark matter density

open access: yesEPJ Web of Conferences, 2012
We study the systematic problems in determining the local dark matter density ρdm(R☉) from kinematics of stars in the Solar Neighbourhood, using a simulated Milky Way-like galaxy.
Read J.I., Lake G., Garbari S.
doaj   +1 more source

Home - About - Disclaimer - Privacy