Results 121 to 130 of about 7,468,635 (299)
Hyper-dependence, hyper-ageing properties and analogies between them: a semigroup-based approach [PDF]
, 2001 In previous papers, evolution of dependence and ageing, for vectors of non-negative random variables, have been separately considered. Some analogies between the two evolutions emerge however in those studies.
SPIZZICHINO, Fabio +4 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Equivalence and bifurcations of finite order stochastic processes [PDF]
This article presents an equivalence notion of finite order stochastic processes. Local dependence measures are defined in terms of joint and marginal densities. The dependence measures are classified topologically using level sets.
Wagener, F.O.O., Diks C.G.H.
core
Commissioning treatment for dependence on prescription and over-the-counter medicines: a guide for NHS and local authority commissioners. [PDF]
, 2013 This guidance sets out PHE’s expectation that support should be available in every area for people with a dependency on prescription or over-the-counter medicines, based on a full assessment of local need.
core
Large-scale estimation of random graph models with local dependence. [PDF]
Comput Stat Data Anal, 2020 Babkin S +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Scaling disturbance instead of richness to better understand anthropogenic impacts on biodiversity.
PLoS ONE, 2015 A primary impediment to understanding how species diversity and anthropogenic disturbance are related is that both diversity and disturbance can depend on the scales at which they are sampled.
Stephen J Mayor +3 more
doaj +1 more source
A Two-Level Alternating Direction Model for Polytomous Items With Local Dependence. [PDF]
Educ Psychol Meas, 2020 Himelfarb I +3 more
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source