Results 81 to 90 of about 7,468,635 (299)
, 1996 In the context of recent interest in extending scalar association measures to local association functions, attention is drawn to the local dependence function, the mixed partial derivative of the log density, proposed by Holland & Wang (1987). We provide
Jones, M. C.
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The Extremal Index of Sub-Sampled Periodic Sequences with Strong Local Dependence
Revstat Statistical Journal, 2003 Let X = {Xn}n≥1 be a T-periodic sequence. We define a family of local dependence conditions D (k) T (u), k ≥ 1, and calculate the extremal index θX from the distributions of k consecutive variables of X.
H. Ferreira, A.P. Martins
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Ubiquitylation-dependent localization of PLK1 in mitosis
Nature Cell Biology, 2013 Polo-like kinase 1 (PLK1) critically regulates mitosis through its dynamic localization to kinetochores, centrosomes and the midzone. The polo-box domain (PBD) and activity of PLK1 mediate its recruitment to mitotic structures, but the mechanisms regulating PLK1 dynamics remain poorly understood. Here, we identify PLK1 as a target of the cullin 3 (CUL3)
Beck, Jochen +11 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Local Linear Fitting Under Near Epoch Dependence: Uniform consistency with Convergence Rates [PDF]
Local linear fitting is a popular nonparametric method in statistical and econometric modelling. Lu and Linton (2007) established the pointwise asymptotic distribution for the local linear estimator of a nonparametric regression function under the ...
Zudi Lu, Degui Li, Oliver Linton
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Socio-Economic Dependence of Peasant to Local Collector on Rice Farming System
Jurnal Ilmu Sosial Mamangan, 2018 The poverty of peasant in Gunung Talang is caused by low income, low education and limited land. The purpose of this research is to analyze the bases of the peasant socio-economic dependence to the local collector (local assemblers) on rice farming ...
Waza Karia Akbar
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Local expression languages for probabilistic dependence
International Journal of Approximate Reasoning, 1995 AbstractA Bayesian belief net is a factored representation for a joint probability distribution over a set of variables. This factoring is made possible by the conditional independence relationships among variables made evident in the sparseness of the graphical level of the net.
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FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Semiparametric Trending Panel Data Models with Cross-Sectional Dependence [PDF]
A semiparametric fixed effects model is introduced to describe the nonlinear trending phenomenon in panel data analysis and it allows for the cross-sectional dependence in both the regressors and the residuals.
Jia Chen, Jiti Gao, Degui Li
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