Results 51 to 60 of about 461,959 (266)

Locality-Aware Distribution Schemes.

open access: yes, 2021
One of the bottlenecks in parallel query processing is the cost of shuffling data across nodes in a cluster. Ideally, given a distribution of the data across the nodes and a query, we want to execute the query by performing only local computation and no communication: in this case, the query is called parallel-correct with respect to the data ...
Sundarmurthy, Bruhathi   +2 more
openaire   +3 more sources

Electron cross talk and asymmetric electron distributions near the Earth's bowshock [PDF]

open access: yesAnnales Geophysicae, 2012
Electron distributions in the magnetosheath display a number of far from equilibrium features. It has been suggested that one factor influencing these distributions may be the large distances separating locations at which electrons with different ...
J. J. Mitchell   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Species traits shape the relationship between local and regional species abundance distributions

open access: yesEcosphere, 2019
The species abundance distribution (SAD) depicts the relative abundance of species within a community, which is a key concept in ecology. Here, we test whether SADs are more likely to either follow a lognormal‐like or follow a logseries‐like distribution
Murilo Dantas de Miranda   +3 more
doaj   +1 more source

Variability of the local φMS values over the gate area of MOS devices

open access: yesJournal of Telecommunications and Information Technology, 2005
The local value distributions of the effective contact potential difference (ECPD or the φMS factor) over the gate area of Al-SiO2-Si structures were investigated for the first time.
Henryk M. Przewłock   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Geometry of Control-Affine Systems

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2009
Motivated by control-affine systems in optimal control theory, we introduce the notion of a point-affine distribution on a manifold X – i.e., an affine distribution F together with a distinguished vector field contained in F.
Jeanne N. Clelland   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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