Results 91 to 100 of about 11,141 (263)

Elecciones municipales en España. dimensiones analíticas y aspectos distintivos de ocho procesos electorales (1979-2007) Elecciones municipales en España. dimensiones analíticas y aspectos distintivos de ocho procesos electorales (1979-2007)

open access: yesPolítica y Sociedad, 2010
The literature on electoral politics has shown a long standing interest in measuring and explaining national and local patters of electoral behaviour over the time but in different degree.
Irene Delgado
doaj  

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

open access: yesAdvanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters   +12 more
wiley   +1 more source

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng   +9 more
wiley   +1 more source

Bilateral SERS‐Microneedle Patch for Co‐Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity

open access: yesAdvanced Science, EarlyView.
Our study introduced a U@mP@Au‐mediated bilateral SERS‐microneedle patch for analyzing glucose levels from ISF and sensitively detecting TB biomarkers from sputum, respectively. This integrated dual‐analyte detecting platform can be used for co‐diagnosis of diabetes mellitus (DM) and tuberculosis (TB) comorbidity, which was demonstrated in ex vivo ...
Xueqin Huang   +12 more
wiley   +1 more source

Noninvasive Characterization of Tumor Heterogeneity in HNSCC: From Clinical Utility to Biological Correlates

open access: yesAdvanced Science, EarlyView.
This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen   +15 more
wiley   +1 more source

Precisely Printing Perovskite Nanocrystals in Glass via Thermoelectric Synergistic Effect

open access: yesAdvanced Science, EarlyView.
Based on the direct migration and enrichment of Cs ions in glass driven by thermoelectric fields, a novel method has been developed to achieve controllable crystallization and patterned distribution of CsPbBr3 PNCs in stable glass. The distribution scale of PNCs strongly depends on the thermoelectric processing conditions (temperature, electric field ...
Zhiheng Miao   +6 more
wiley   +1 more source

Le elezioni amministrative del 13 ottobre 2019 in Ungheria. Il Fidesz vince nella provincia ma perde Budapest: è sfida aperta per le politiche del 2022

open access: yesNuovi autoritarismi e democrazie: diritto, istituzioni, società, 2019
On October 13, local elections were held in Hungary and the political outcome is mixed. Fidesz strengthens its consensus throughout the nation, however, opposition parties celebrate a stunning victory in Budapest and in many other cities.
Cristiano Preiner
doaj  

The Dynamics and Challenges of Election and Democratic Consolidation in Nigeria: A Study of 2019 and 2023 Gubernatorial Election in Kano State

open access: yesActa Politica Polonica
This study examines the Elections and Democratic Consolidation in Nigeria: A Study of 2019 And 2023 Gubernatorial Election in Kano State. Multi-stage cluster sampling procedure was used in sampling population for this study.
Abdulrasheed Abdulyakeen   +1 more
doaj   +1 more source

mTORC2 Phosphorylation of GSDME‐N Drives Cullin4B‐Mediated Proteasomal Degradation to Suppress Pyroptosis and Confer Radioresistance in Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Radioresistance severely limits the efficacy of therapies for small cell lung cancer (SCLC). This study reveals a novel mechanism of resistance driven by the active suppression of pyroptosis. Specifically, the mTORC2 complex directly phosphorylates GSDME‐N and promotes its CUL4B‐mediated ubiquitination and proteasomal degradation.
Qing‐qing Xu   +11 more
wiley   +1 more source

Long‐Term Ambient Benzene Exposure and Brain Disorders Among Urban Adults: Effect Modification by Genetic Susceptibility and Potential Mediation by Plasma Proteins

open access: yesAdvanced Science, EarlyView.
Low‐level ambient benzene exposure is associated with increased risks of multiple brain disorders in urban adults. Genetic susceptibility modifies these associations, while plasma proteomics points to potential biological pathways linking benzene exposure to adverse brain health.
Jianhui Guo   +10 more
wiley   +1 more source

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