Results 161 to 170 of about 8,025,626 (297)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

DOLD-Net: Dense occluded livestock detection via global-local feature collaboration. [PDF]

PLoS One
Jia K, Chai Y, Chen B, Gao Z.
europepmc   +1 more source

Structured Cluster Detection from Local Feature Learning for Text Region Extraction. [PDF]

Entropy (Basel), 2023
Lin HY, Hsu CY.
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

GADF-enhanced global-local feature network for wearable sensor-based cow behavior recognition. [PDF]

Front Vet Sci
Wang C.
europepmc   +1 more source

Few-Shot Text Classification with Global-Local Feature Information. [PDF]

Sensors (Basel), 2022
Wang D, Wang Z, Cheng L, Zhang W.
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

The local capacity, local community and local governance dimensions of sustainability in Australian Local Government

, 2011
The problem of the `financial sustainability of individual local councils represents the most significant policy question at issue in contemporary debate on Australian local government.
Grant, BJ, Dollery, B, Crase, L
core  

Lightweight Monocular Depth Estimation with Local Feature Enhancement Modules and Guided Data Augmentation. [PDF]

Sensors (Basel)
Lee JY, Kwon SK.
europepmc   +1 more source

High-Speed and Accurate Diagnosis of Gastrointestinal Disease: Learning on Endoscopy Images Using Lightweight Transformer with Local Feature Attention. [PDF]

Bioengineering (Basel), 2023
Wu S, Zhang R, Yan J, Li C, Liu Q, Wang L, Wang H.   +6 more
europepmc   +1 more source