Results 161 to 170 of about 193,471 (315)

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Can Partnerships offer an Alternative Mode of Governance within the Contemporary Local Political Domain? An Initial Approach

This paper attempts to identify if partnerships between public, private and voluntary/community organisations provide an adequate mode of governance in today's local political domain.
Apostolakis, Christos
core  

Local governance dynamics in the Colombian health system: an exploratory cross-sectional study among public health sector officials. [PDF]

J Public Health Policy
Losada-Trujillo N, Eslava-Schmalbach J, Guarnizo-Herreño CC.   +2 more
europepmc   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Community Governance – Where did it all go Wrong?

, 2012
Over the past decade there has been much debate challenging the approach that New Labour took on tackling social and economic division across Britain. Coupled with this debate, questioning the merit of community governance, British society in 2006 was ...
Halsall, Jamie
core  

One health rapid qualitative assessment: Exploring local governance gaps in Tanzania. [PDF]

One Health
Rubin O, Nyanda SS, Norström M.
europepmc   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Political conflict, community forest governance and local livelihoods in Nepal

, 2011
Nepal is one of the world’s richest biodiversity hotspots with varied climate, geography and ecosystems. The majority of people in Nepal’s hills and mountains still depend heavily on forest resources for their livelihood and wellbeing. However, since the
Adhikari, Jay Ram
core  

Strengthening Community-Based Mental Health Through Local Governance and <i>Barangays</i> in the Philippines. [PDF]

Inquiry
Alibudbud R.
europepmc   +1 more source