Results 31 to 40 of about 193,471 (315)

Cardiovascular risk factor mediation of the effects of education and Genetic Risk Score on cardiovascular disease: a prospective observational cohort study of the Framingham Heart Study

open access: yesBMJ Open, 2021
Objectives Level of education and genetic risk are key predictors of cardiovascular disease (CVD). While several studies have explored the causal mechanisms of education effects, it remains uncertain to what extent genetic risk is mediated by established
Katie L Powell   +2 more
doaj   +1 more source

Operationalising local governance in Kilimanjaro

open access: yes, 2003
Decentralisation is a policy feature common to many African countries. Local governance is therefore gaining in relevance, though not yet in clarity. Based on the experience of a development project in Kilimanjaro, Tanzania, the article examines the case
van Klinken, Rinus
core   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa   +8 more
wiley   +1 more source

Leistungserbringung in kleinen Gemeinden: Eigenerstellung oder Auslagerung?

open access: yesYearbook of Swiss Administrative Sciences, 2023
Die Entscheidung, ob eine Leistung in kleinen Gemeinden ausgelagert oder in Eigenerstellung erbracht werden soll, erfolgt vor allem unter dem Druck zur Effizienzsteigerung und gleichzeitigen Einsparungen der Kosten in den Verwaltungen, sich wandelnden ...
Martina Möckli   +2 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Local government scrutiny and governance: Limits and possibilities [PDF]

open access: yes, 2007
The central focus of this thesis is the role of scrutiny within the modernised system of local government and governance. The study was carried out from an insider-research perspective within the scrutiny team of a unitary authority. The scrutiny process
Wistow, Jonathan
core  

Trends in Local Ecosystem Governance

open access: yesFrontiers in Climate, 2021
The physical and biological factors that together determine ecosystem structure and function will be subject to enormous pressures under future climate regimes.
Karrigan Bork, Keith Hirokawa
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Supporting Survivor‐Centered Care Through Digital Health Integration

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Survivors of childhood cancer face barriers to receiving guideline‐based, long‐term follow‐up care. Two digital tools, Passport for Care (PFC) and Cancer SurvivorLink (SurvivorLink), address complementary gaps by enabling tailored survivorship care plan (SCP) generation, updating, storage, and sharing.
Jordan G. Marchak   +15 more
wiley   +1 more source

“Invalid busyness” behaviors of a few grassroots cadres: Evidence from normative explanation

open access: yesFrontiers in Psychology, 2022
Effective grassroots governance is the foundation for the stability of state power, but the “invalid busyness” behavior of a few grassroots cadres has seriously deteriorated the local political ecology.
Cheche Duan   +4 more
doaj   +1 more source

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