Results 61 to 70 of about 193,471 (315)

Pedestrians’ infrastructure design and everyday mobility navigation in urban Wa, Ghana

open access: yesDiscover Cities
Despite the effort in safeguarding pedestrians through the provision of pedestrians’ infrastructure, studies have shown that motorists and pedestrians crash are yet occassioned by non-utilization of existing pedestrians’ infrastructure in cities of the ...
Nicholas Kombonaah   +2 more
doaj   +1 more source

Corruption, regionalization and local governance [PDF]

open access: yesSociološki Pregled, 2002
Corruption is old almost as human societies and it was developed simultaneously with enlargement of social and political power, bureaucracy and involvement of the state into market transactions.
Vuković Slobodan V.
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A Retrospective Analysis of Severe Injury Patients in The Hub and Spoke Centres in The Province of Alessandria

open access: yesEpidemiology, Biostatistics and Public Health
Trauma is one of the leading causes of death in Western countries and results in severe health, economic, and social consequences due to residual disabilities.
Riccardo Mazzucco   +8 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

How do career expectations and job preparation affect youth job satisfaction? An empirical analysis based on underdeveloped regions in China

open access: yesFrontiers in Psychology
Against the backdrop of intensified labor market competition, youth in underdeveloped regions face heightened structural constraints. It is crucial to understand the specific characteristics of their career expectations and job preparation, as well as ...
Xin Zhong, ZeKun Wang
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Climate change policy, conflict and transformative governance [PDF]

open access: yes, 2013
Climate change is the behemoth of our age. It defies description, is too large to comprehend, and what we do understand about it is often terrifying. This is for many, a good reason to stop thinking about it or, like Scarlett O’Hara, decide to “think ...
Melissa Nursey-Bray
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Home - About - Disclaimer - Privacy