Results 171 to 180 of about 1,689,777 (305)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Responsiveness to City Service Requests, Life Satisfaction, and Horizontal Inequality: Does Good Local Governance Improve Subjective Well-Being for All? [PDF]

Int J Environ Res Public Health
Tharakan DPL, Ford TN.
europepmc   +1 more source

Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore

Advanced Functional Materials, EarlyView.
To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul, Archith Rayabharam, Lisa Almonte, Eveline Rigo, Joshy Joseph, Ashutosh Kumar, Zhuxin Dong, Narayana Aluru, Gregory Timp   +8 more
wiley   +1 more source

Prices, availability, and affordability of selected medicines for asthma management in Nigeria: a nationwide study. [PDF]

BMC Health Serv Res
Amorha KC, Eze FN, Uzuh IF, Nwani SP, Iganga JC, Eze CE, Ifeanyi CR, Agubata AA, Ibenekwu CS, Aniebonam IC, Ani AC, Ezenwafor CC, Omene EC, Chukwuwa OM, Ezeala CP, Mbakamma CE, Nworah CR, Udoji MD, Ochie KM, Sabastine RN, Obi OC, Oparaocha RN, Okoye CR, Eze OP.   +23 more
europepmc   +1 more source

SHIFTING ROLES OF LOCAL GOVERNMENTS IN THE UNITED KINGDOM

Afyon Kocatepe Üniversitesi İktisadi ve İdari Bilimler Fakültesi Dergisi, 2010
Birleşik Krallık'ta, son yirmi yılda yerel yönetimlerin belirgin bir değişim süreci içinde olduğu gözlenmektedir. Söz konusu süreçte yerel yönetimlerde gözlemlenen yapısal, finansal ve yönetsel değişimlerde; doğrudan yerel kamu hizmeti verme sorumluluğunun azaldığı ve bunun yerine vatandaş odaklılığı, kaliteli hizmeti hedef alan, özel sektörü ...
openaire   +3 more sources

Multi‐Faceted Binder Enhancement via Slurry‐Applicable Thiol‐Ene Click Chemistry for Low‐Pressure‐Operable All‐Solid‐State Batteries

Advanced Functional Materials, EarlyView.
Cross‐linked binders with enhanced resiliencies under low operating pressures are designed via in situ thiol‐ene click reactions within slurries. Cross‐linking improves the Young's moduli and elasticities of the styrene‐butadiene rubber binders, effectively mitigating interparticle delamination within the composite cathodes induced by volumetric ...
Young Joon Park, Kyu Tae Kim, Seunggoo Jun, Jong Seok Kim, Jaehyun Yoon, Cheol Bak, Yong Min Lee, Dong Hyeon Kim, Ji Young Kim, Yoon Seok Jung   +9 more
wiley   +1 more source

Epidemiology and Risks Survey of <i>Onchocerca volvulus</i> Infection in Igbo-Eze North Local Government Area, Enugu State, Nigeria. [PDF]

Trop Med Infect Dis
Aniaku IE, Onyishi GC, Nwosu CG, Ngwu GI, Okeke CJ, Oraneli UB, Otuu CA, Akobe NA, Nnama AU, Onah KI.   +9 more
europepmc   +1 more source

Devolution and Fiscal Decentralisation [PDF]

Fiscal decentralisation represents the transfer of resources from higher to lower levels of government usually accompanied by an enhancement in responsibilities and functions of sub- national governments and greater autonomy in their budget making and ...
Aisha Ghaus-Pasha, Hafiz A. Pasha
core  

Golden‐Ratio–Guided Aperiodic Architected Metamaterials with Simultaneously Enhanced Strength and Toughness

Advanced Functional Materials, EarlyView.
Guided by the golden ratio, a class of aperiodic architected metamaterials is introduced to address the intrinsic trade‐off between strength and toughness. By unifying local geometric heterogeneity with global order, the golden‐ratio‐guided aperiodic architecture promotes spatial delocalization of damage tolerence regions, leading to more tortuous ...
Junjie Deng, Xinxin Wang, Ruochao Zhao, Zhendong Li, Kai Liu, Ke Yuan, Jia An, Xinwei Li, Chee Kai Chua, Zhonggang Wang   +9 more
wiley   +1 more source

Exploiting Two‐Photon Lithography, Deposition, and Processing to Realize Complex 3D Magnetic Nanostructures

Advanced Functional Materials, EarlyView.
Two‐photon lithography (TPL) enables 3D magnetic nanostructures with unmatched freedom in geometry and material choice. Advances in voxel control, deposition, and functionalization open pathways to artificial spin ices, racetracks, microrobots, and a number of additional technological applications.
Joseph Askey, Arjen van den Berg, Sandra Ruiz Gomez, Claire Donnelly, Dirk Grundler, Sam Ladak   +5 more
wiley   +1 more source