Results 81 to 90 of about 7,800,970 (362)
The Debt Consolidation of Hungarian Local Governments [PDF]
The total debt of Hungarian local governments accumulated during the 2002–2008 period was consolidated in full by the government between 2011 and 2014.
Lentner, Csaba
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Empowering Local Governments? The LOKAL+ project in Haiti
In Haiti, the traditional centralization of power in Port-au-Prince has far-reaching effects, one of which is the limited influence of ordinary citizens on holding local officials accountable for providing basic services like trash removal ...
Tonny, Joseph
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Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Durban, South AfricaThe Durban Adaptation Charter complements the “Global Cities Covenant on Climate - the Mexico City Pact” and ‘carbon n’ Cities Climate Registry through which cities and other local governments measure, report and verify their GHG ...
ICLEI - Local Governments for Sustainability
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The Impact of Outsourcing and Full-Cost pricing initiatives on Local governments
Outsourcing has become a regular practice in the Australian public sector, including in local governments, which have increasingly used outsourcing mechanisms to reduce costs and deliver services (Blank & Niaounakis 2021).
Soar, Jeffrey, Manton, Carl, Lyons, Ben
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Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Myopic or constrained by balanced-budget-rules? The intertemporal spending behavior of Norwegian local governments [PDF]
The paper analyzes the intertemporal spending behavior of Norwegian local governments with particular attention to liquidity constraints imposed by balanced-budget-rules (BBRs). The main findings are: (i) On average, local government spending behavior is
Per Tovmo, Lars-Erik Borge
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Sustainability Management and Local Governments
After highlighting the breadth and complexity of the concept of sustainability and highlighting the role of local authorities in sustainable development, this chapter aims to interpret how sustainability management can consider the concept of financial ...
Fabio De Matteis, Daniela Preite
core +1 more source

