Results 191 to 200 of about 17,303,555 (314)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

On the Structure of Locally Compact Groups [PDF]

Proceedings of the National Academy of Sciences, 1949
openaire   +3 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

A Novel Gelatin Hydrogel-Based Drug-Delivery System Promotes Antimicrobial Efficacy in a Pyogenic Spondylodiscitis Rat Model. [PDF]

JOR Spine
Miyazaki K, Kanda Y, Yurube T, Takeoka Y, Tsujimoto T, Ohnishi H, Matsuo T, Ryu M, Kumagai N, Kuroshima K, Hiranaka Y, Tabata Y, Kuroda R, Kakutani K.   +13 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Co-Designing Physical Activity Programmes: A Participatory Research Study With Culturally Diverse Women and Local Government. [PDF]

Health Promot J Austr
Casey M, Porter JE, Eime R.
europepmc   +1 more source

Traveller Accommodation Expert Review: Prepared by an independent Expert Group on behalf of the Minister of the Department of Housing, Planning and Local Government

, 2019
This report sets out an integrated set of recommendations intended to improve the effectiveness of the arrangements for providing accommodation for members of the Traveller community, which were established by the Housing (Traveller Accommodation) Act ...
Norris, Michelle, Joyce, David, Norton, Conor   +2 more
core  

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Infection and quality of life after local or full scalp shaving in microsurgical treatment for unruptured intracranial aneurysm sited in anterior circulation. [PDF]

Chin Neurosurg J
Hou Y, Feng Y, Zhang J, Zheng K, Zhang J, Liu Q, Liu P, Zhang Y, Wu J, Wang S, Zhao D, Chen S.   +11 more
europepmc   +1 more source

Arcs in Locally Compact Groups [PDF]

Proceedings of the National Academy of Sciences, 1950
openaire   +2 more sources