Results 101 to 110 of about 5,830,879 (341)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Standard comparison of local mental health care systems in eight European countries

Epidemiology and Psychiatric Sciences, 2017
Aims. There is a need of more quantitative standardised data to compare local Mental Health Systems (MHSs) across international jurisdictions. Problems related to terminological variability and commensurability in the evaluation of services hamper like ...
M. Gutiérrez-Colosía, L. Salvador-Carulla, J. Salinas-Pérez, C. García-Alonso, Jordi Cid, D. Salazzari, I. Montagni, F. Tedeschi, Gaia Cetrano, Karine Chevreul, J. Kalseth, G. Hagmair, C. Straßmayr, A. Park, R. Sfectu, Taina Ala-Nikkola, J. González-Caballero, L. Rabbi, Birgitte Kalseth, F. Amaddeo, F. Endel, H. Katschnig, Sonja Scheffel, B. Weibold, T. Matosevic, D. McDaid, Kristian Wahlbeck, Niklas Gronlund, Irja Hemmila, G. Joffe, Jutta Jarvelin, R. Kontio, Maili Malin, P. Näätänen, Sami Pirkola, Minna Sadeniemi, E. Sailas, Marjut Vastamaki, M. Brunn, A. Prigent, V. Donisi, L. Grigoletti, Oyvind Hope, Jon Magnussen, J. Cabasés, Ana Fernández, A. Gabilondo, Á. Iruin, E. Jordà, Cristina Molina, Emma Motrico, Bibiana Prat, Carlos Pereira, Jose Juan Uriarte, Lucian-Liviu Albu, M. Ciumăgeanu, N. Chiriac, Dan Ghenea, Simona Musat, Cristian Oana, A. Paziuc, C. Păuna   +61 more
semanticscholar   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

The roles and responsibilities of local public health systems in urban health [PDF]

Journal of Urban Health, 1998
In recent years, policy analysts have paid much attention to the precarious state and uncertain future of local public health departments and so-called safety net providers, usually treating each separately. This paper explores the ways in which these systems are converging, are adapting to a changing health marketplace, and are interacting with new ...
openaire   +2 more sources

Local Food Systems: Concepts, Impacts, and Issues [PDF]

This comprehensive overview of local food systems explores alternative definitions of local food, estimates market size and reach, describes the characteristics of local consumers and producers, and examines early indications of the economic and health ...
Clark, Shellye, Da Pra, Michelle, Hand, Michael S., Lohr, Luanne, Low, Sarah A., Martinez, Stephen W., Newman, Constance, Pollack, Susan L., Ralston, Katherine L., Smith, Travis A., Vogel, Stephen J.   +10 more
core   +1 more source

Increasing Safety in America's Public Schools [PDF]

, 2001
As the Public Education Network (PEN) and its member local education funds (LEFs) are committed to creating systems of public education that result in high achievement for every child, we believe that equal opportunity, access to quality public schools ...
Beth Bacon
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A saúde indígena no processo de implantação dos Distritos Sanitários: temas críticos e propostas para um diálogo interdisciplinar

Cadernos de Saúde Pública
A proposta do presente trabalho é a de expor, a partir das experiências dos autores, alguns problemas que se apresentam no atual processo de implantação dos distritos sanitários indígenas, relacionados à organização dos serviços de saúde segundo o ...
Renato Athias, Marina Machado
doaj  

Migrant health in Italy: a better health status difficult to maintain—country of origin and assimilation effects studied from the Italian risk factor surveillance data

Population Health Metrics, 2019
Background Many studies on migrant health have focused on aspects of morbidity and mortality, but very few approach the relevant issues of migrants’ health considering behavioral risk factors.
Stefano Campostrini, Giuliano Carrozzi, Santino Severoni, Maria Masocco, Stefania Salmaso, WHO Migration Health Programme, Office of the Regional Director, WHO Regional Office for Europe, the PASSI National Coordinating group   +6 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source