Results 151 to 160 of about 14,031,347 (347)

Archaeological Reconnaissance in Tarbagatai (East Kazakhstan) Using Satellite Imagery Data: methodology and results of research

open access: yesАрхеология евразийских степей
The paper deals with the results of an archaeological reconnaissance based on satellite imagery in the Tarbagatai mountain range and its foothills (Abai region, Republic of Kazakhstan).
Andrey A. Pushkarev
doaj   +1 more source

The Development of Historical Instruction/Teaching Material in Senior High Schools Based on Local History with SOI Approach [PDF]

open access: yes, 2013
Purpose: The purpose of this research is to develop more comprehensive model of historical instructional materials that is a model of local history-based teaching materials and oriented to local historical events. The method used in the development
Djono,
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Chronicle Kozelsk. Issues and stages of archaeological investigation

open access: yesПоволжская археология, 2015
The article is devoted to the history of archaeological investigations of the ancient Russian town of Kozelsk, destroyed by Batu Khan in 1238. The problem of the annalistic town localization arose in 1992, following the first large-scale excavations in ...
Massalitina Galina A., Boldin Igor V.
doaj  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

A Folk Tale of a Poor Man [PDF]

open access: yes, 2009
Bstan 'dzin tells a folk tale in which a poor man outsmarts a rich manThis collection of 77 audio files focuses on weddings and weddings speeches but also contains: folk tales, folk songs, riddles, tongue twisters, and local history from Bang smad ...
Bkra shis bzang po
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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