Results 151 to 160 of about 2,033,218 (305)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

History of Bettsville, Ohio 1984

open access: yes, 1984
A book describing the history of Bettsville, Ohio in Seneca County, Liberty Township.
Durrett, John E.
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Historical geography and local history

open access: yesNew Contree
Historical geography and local history originated in two separate parent subjects, geography and history. This is reflected in het the approaches they adopt respectively. They share, however, a common field of investigation: the development of an area or region through time, which explains why in the last twenty-five years the differences between them ...
openaire   +2 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

History of Tiffin's Breweries and Bottling Works

open access: yes, 1970
This history, written by Joseph Terry, recalls the history of Tiffin, Ohio's breweries and bottlers beginning in the year 1835. The breweries named in the book are Tiffin Brewing Company (Clinton Brewery), the City Brewery, Hubach Brewery, Allen's ...
Terry, Joseph
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Junior Order United American Mechanics History

open access: yes, 1929
This Junior Order United American Mechanics History gives the background and history of the Junior Home in Lexington, North Carolina and was thus dedicated to the "little children" who lived at the Tiffin, Ohio, and Lexington locations. The cover is dark
Clark, Paul F.
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

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