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The European Open Science Cloud (EOSC) versus the single Research Institution. Drawing the scenario at local level. Workshop sull\u27Open Science, Venezia 4 Settembre 2017

The slides, realized in the seminar "The European Open Science Cloud (EOSC) versus the single Research Institution. Drawing the scenario at local level" were presented and discussed during the "Workshop on Open Science" (Venice, 4 September 2017 ...
Occioni, Marisol, Bianchi , Elena, Vedaldi, Maurizio, Zane, Antonella, Celentano, Augusto, Budroni, Paolo, Toniolo, Sandra   +6 more
core  

Demographic sensitivity inside the local authorities [PDF]

The knowledge of the administrated population it is not wll appreciated at local level by the Administrators (Majors, Councillors, Public Servants). The attention is more devoted to political items and the sensitivity for the numbers of the population is
Enrico Todisco, Raimondo Cagiano de Azevedo   +1 more
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Enhanced Recovery After Surgery (ERAS) Outcomes After Liver and Pancreas Surgery Based on Regional Perioperative Pain Modalities. [PDF]

Cureus
Sulciner ML, Wang J, Fairweather M, Molina G, Clancy TE.   +4 more
europepmc   +1 more source

Kilnerton Training Institution - Teacher assisting secondary school children

The Kilnerton Training Institution, affiliated to the Methodist Church of Southern Africa, was established in 1886 in the small suburb of Weaving Park, Pretoria. The Institution was named after Rev.

core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Representation learning to advance multi-institutional studies with electronic health record data from US and France. [PDF]

Nat Commun
Zhou D, Tong H, Wang L, Liu S, Xiong X, Gan Z, Romain G, Hejblum BP, Liu YC, Hong C, Bonzel CL, Cai T, Pan K, Ho YL, Costa L, A Panickan V, Gaziano JM, Mandl KD, Jouhet V, Thiebaut R, Xia Z, Cho K, Liao K, Cai T.   +23 more
europepmc   +1 more source

The European Open Science Cloud (EOSC) versus the single Research Institution. Drawing the scenario at local level. Executive summary, Venice 5 September 2017

Il documento è stato prodotto come risultato di: a) il seminario su “The European Open Science Cloud (EOSC) versus the single Research Institution.
Occioni, Marisol, Bianchi, Elena, Vedaldi, Maurizio, Zane, Antonella, Celentano, Augusto, Budroni, Paolo, Toniolo, Sandra   +6 more
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source