Results 181 to 190 of about 425,228 (311)

Definitive proton therapy for unresectable trunk soft tissue sarcoma: a single-institution prospective registry-based cohort study. [PDF]

Clin Transl Radiat Oncol
Sudo S, Nakajima K, Ogino H, Yokoyama Y, Sunagawa M, Iwata H, Hattori Y, Hayashi K, Toshito T, Hiwatashi A.   +9 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Twelve-Month Metastatic State as a Landmark-Based Prognostic Stratifier in Metastatic Sarcoma. [PDF]

Cancers (Basel)
Loupasis T, Ruthenberg J, Vogel B, Schärer M, Schelling G, Heesen P, Studer G, Fuchs B, On Behalf Of The Swiss Sarcoma Network.   +8 more
europepmc   +1 more source

8. Local Institutions

, 2005
Stella Williams, Katia Frangoudes, José J. Pascual-Fernández   +2 more
openaire   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Correction: IMF deposition ceRNA network analysis and functional study of HIF1a in yak. [PDF]

Front Vet Sci
Luo M, Wang H, Zhang J, Yixi K, Shu S, Fu C, Zhong J, Peng W.   +7 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Point-Counterpoint: The "obsoletogram"-are annual hospital antibiograms still relevant? [PDF]

J Clin Microbiol
Weiss ZF, Basu SS.
europepmc   +1 more source

A Strategic Orientation Model for the Turkish Local e-Governments

Increased environmental uncertainty and complexity along with budget constraints requires public organizations to manage strategically as never before.
Aykut, Arslan
core