Results 31 to 40 of about 64,894 (298)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Brussel te midden van de stadslegendes?

open access: yesBrussels Studies, 2011
This article presents urban legends told in Brussels which reflect an urban imagination crossed with local characteristics. Presented as news items although their truthfulness is questionable, these stories mentioning Brussels tell of attacks or harm ...
Aurore Van de Winkel
doaj   +1 more source

Local Colors in Adipati Waringin Legends in Cirebon Regency

open access: yesInternational Journal of Multicultural and Multireligious Understanding, 2021
This study aims to reveal the local colors in the Adipati Waringin Legend in the Cirebon Regency. This research was a descriptive qualitative study with an ethnographic approach. In obtaining data, researchers used interview, observation, and documentation as techniques. These data were processed and tested using triangulation.
Nurul Atikah Fauzi   +2 more
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Jutud peidetud varandustest Pärimus ja meedia [PDF]

open access: yesMäetagused, 2003
In the 1920s-1940s, Estonian press publish numerous descriptions of search for treasures and archaeological findings. Some published classical legends from the Estonian Folklore Archives.
Mare Kalda
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Primele mențiuni referitoare la prezența strămoșilor romilor/țiganilor moldoveni în spațiul carpato-nistrean conservate în legendele locale și consemnate în publicații

open access: yesRevista de Etnologie şi Culturologie, 2017
Currently, Roma history is marked by an interdisciplinary variety of „white spots” which must to be gradually removed by fundamental research into social and humanitarian sciences. In this thnological study, for fragmentary elucidation of aspects related
Ion Duminica
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

LEGENDA-LEGENDA KERAMAT DI KAWASAN SANCANG KABUPATEN GARUT (Studi tentang Kearifan Lokal)

open access: yesPatanjala: Jurnal Penelitian Sejarah dan Budaya, 2013
Abstrak Dalam studi-studi kebudayaan, legenda menempati posisi yang cukup penting mengingat fungsi dan peranannya yang sangat penting dalam kehidupan masyarakat.
Rosyadi .
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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