Results 41 to 50 of about 307,243 (226)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

PARTICLE SWARM OPTIMIZATION WITH INDIVIDUALLY BIASED PARTICLES FOR RELIABLE AND ROBUST MAXIMUM POWER POINT TRACKING UNDER PARTIAL SHADING CONDITIONS

Eurasian Physical Technical Journal, 2020
Efficient power control techniques are an integral part of photovoltaic system design. One of the means of managing power delivery is regulating the duty cycle of the DC to DC converter by various algorithms to operate only at points where power is ...
K. Baktybekov, A. Kurmanbay, K. Sakhanov, A. Syzdykov, A. Mukhamediyev   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Experimental validation of effective zebra optimization algorithm-based MPPT under partial shading conditions in photovoltaic systems

Scientific Reports
This study introduces a novel approach for analyzing photovoltaic (PV) systems that employ block lookup tables for speedy and efficient simulation. It introduces an innovative method for tracking the Global Maximum Power Point (GMPP) by utilizing Zebra ...
Feriel Abdelmalek, Hamza Afghoul, Fateh Krim, Djallal Eddine Zabia, Hafedh Trabelsi, Mohit Bajaj, Ievgen Zaitsev, Vojtech Blazek   +7 more
doaj   +1 more source

MPPT algorithm based on modified remora optimization algorithm for photovoltaic systems under partial shading conditions

Journal of Mechatronics, Electrical Power, and Vehicular Technology
The increasing electricity demand, driven by the growing human population, has led to the need for efficient backup power sources. Solar panels are one of the renewable energy sources that have been widely developed because they only require solar energy
Moh. Zaenal Efendi, Akhmad Adnaurrosyid, Muhammad Nizar Habibi, Rachma Prilian Eviningsih, Novie Ayub Windarko, Mentari Putri Jati   +5 more
doaj   +1 more source

Maximum Power Point Tracking Technology of Photovoltaic Array under Partial Shading Based On Adaptive Improved Differential Evolution Algorithm

Energies, 2020
In the case of partial shading conditions, there will be more than one maximum power point (MPP) in photovoltaic (PV) array. The traditional maximum power point tracking (MPPT) methods are easy to get in the local maximum power point (LMPP) and fail ...
Peng Zhang, Huibin Sui
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source