Results 101 to 110 of about 922,499 (265)
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Erciyes İletişim DergisiDijitalleşme çağında, yerel medya coğrafi sınırları aşarak, belirli bölgelerle sınırlı kalmak yerine küresel bir kitleyi hedeflemektedir. İnternet teknolojileri, yerel medyanın haberlere daha hızlı ulaşmasını sağlamış olsa bile güvenilirlik sorunlarını ...
Ferhat Kaçar
doaj +1 more source
The reinvention of “locality”: Imagining the local society with local media
Communication and the PublicIn this essay, we draw on the history of internet-based local media at the county level in China to investigate the social implications of the internet for the local society. We take a “formative” approach and analyze the social processes of the reinvention of “locality” from the spatial, economic, and political aspects.
Wei Wang, Huixin Guan
openaire +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Bölge Çalışmaları DergisiThe former government of the Islamic Republic of Afghanistan (hereinafter referred to as the Islamic Republic) and the Islamic Taliban Movement (hereinafter referred to as the Taliban) attached great deal of importance to media coverage of the intra ...
Samiul Haq Qayomi, Md. Nazmul Islam
doaj
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
FEBS Open Bio, EarlyView.Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
International Journal of CommunicationDigital news media have struggled to find the most sustainable business model to survive and thrive in recent years. Current research has paid little attention to this problem at the local level in non-Western and peripheral media systems.
Antoine Faure +3 more
doaj
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Overweight and Obesity in Local Media: An Analysis of Media Coverage in CDC-Funded Communities. [PDF]
Prev Chronic Dis, 2017 Thomas CN +4 more
europepmc +1 more source