Results 181 to 190 of about 6,352,807 (298)

TSTScope Unifies Single‐Cell Multi‐Omics to Identify Functional T Cell States Predictive of Immunotherapy Response

Advanced Science, EarlyView.
TSTScope is an interpretable AI framework that integrates single‐cell transcriptomes with TCR information through curated gene‐program constraints. By linking receptor context to functional T cell states, it reveals response‐associated tumor‐specific T cell programs in lung cancer immunotherapy cohorts and defines an MPR score associated with ...
Shiwei Cao, Jinyu Cheng, Feng‐ao Wang, Chenxin Yi, Jiajun Chen, Keyue Wang, Lulu Liu, Junwei Liu, Yixue Li   +8 more
wiley   +1 more source

Synchronous retroperitoneal and mesenteric dedifferentiated liposarcoma: case report of a challenging rare disease and literature review. [PDF]

J Surg Case Rep
Giambusso M, Di Mattia P, Graziano GMP, Licciardello A, Centonze DC.   +4 more
europepmc   +1 more source

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

Advanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao, Wei Gu, Yimin Ren, Chenfei Lu, Wanzhi Cai, Junnan Lu, Zhongyuan Bao, Yanan Zhou, Rong Li, Ke Jin, Chao Chen, Hongxiang Wang, Lei Xu, Juxiang Chen   +13 more
wiley   +1 more source

Case Report: Revealing the truth: how superficial ossification mimics cutaneous tuberculosis in ossifying fibromyxoid tumor. [PDF]

Front Oncol
Wang C, Li H.
europepmc   +1 more source

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

Advanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao, Na Zhou, Ruotong Liu, Xiaofei Li, Jian Li, Fuzhong Xue, Qingzhen Hou   +6 more
wiley   +1 more source

Intraoral desmoplastic melanoma requiring radical multidisciplinary resection and free flap reconstruction: case report and literature review. [PDF]

J Surg Case Rep
Álvarez Vásquez FA, Zaraza Duarte JP, Garzón Bautista LA, Rodríguez Mantilla IE, Cala Gómez ND, Marulanda Grajales D, Guataquira Sierra NC.   +6 more
europepmc   +1 more source

Argon plasma coagulation therapy after submucosal injection of normal saline solution for local recurrence of large nonampullary duodenal neoplasm

VideoGIE, 2016
Tomoyuki Hayashi, MD, Miyabi Miura, MD, Hajime Takatori, MD, PhD, Kazuya Kitamura, MD, PhD, Tatsuya Yamashita, MD, PhD, Shuichi Kaneko, MD, PhD   +5 more
openaire   +4 more sources

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Real-Time Assessment of Endoscopic Ultrasound-Guided Ethanol Injection for Pancreatic Neuroendocrine Neoplasm Using Superb Microvascular Imaging. [PDF]

Dig Endosc
Inoue T, Yano M, Ito K.
europepmc   +1 more source

Design and Application of Nanozymes: Current Trends and Cutting‐Edge Breakthroughs

Advanced Science, EarlyView.
Kelong Fan, Hui Wei, Xiyun Yan
wiley   +1 more source