Results 61 to 70 of about 185,531 (315)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Proliferating pilomatricoma - Case report [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2015
Proliferating pilomatricoma is proliferative, rare tumor variant of pilomatricoma. It is a benign neoplasm of hair matrix that can have potentially involve local recurrence.
Rogerio Nabor Kondo   +5 more
doaj   +2 more sources

Management and treatment of sinonasal inverted papilloma [PDF]

open access: yes, 2015
Aims: The aim of this paper is to describe the surgical experience of 35 patients with Inverted Papilloma (IP) of paranasal sinuses and its recurrence rate after a year of follow-up.
Agrillo, Alessandro   +6 more
core   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Odontogenic Myxoma Of The Maxilla: A Clinical Case Report And Review Of Literature [PDF]

open access: yes, 2013
Odontogenic myxomas are rare benign mesenchymal  tumours of head and neck with a potential for  local infiltration and recurrence. They appear to originate from the dental papilla, follicle or periodontal ligament in mandible and less commonly the ...
Bhardwaj, Vikram   +3 more
core   +2 more sources

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Analysis of Factors Affecting Local Tumor Progression of Colorectal Cancer Liver Metastasis after Radiofrequency Ablation

open access: yes대한영상의학회지, 2017
Purpose The purpose of this study was to evaluate the independent predictive factors for local tumor progression (LTP) of colorectal liver metastasis (CRLM) after radiofrequency ablation (RFA).
Seong Hee Jeon   +4 more
doaj   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Textiloma Mimicking a Recurrent High-Grade Astrocytoma: A Case Report

open access: yesJournal of Neurological Surgery Reports, 2020
Introduction Textiloma (Txm) is a nonmedical term that has been given to foreign body-related inflammatory pseudotumor arising from retained nonabsorbable cotton matrix that is either inadvertently or deliberately left behind during surgery, which may ...
Esteban Jaramillo-Jiménez   +9 more
doaj   +1 more source

A rare case of solitary fibrous tumor of the temporal region: 7-year-follow-up clinical-radiographic evaluation and literature review

open access: yesOral and Maxillofacial Surgery Cases, 2022
Solitary fibrous tumor is a rare spindle-cell neoplasm of mesenchymal origin. In head and neck region, the tumors present slow-growing masses, often with local compressive symptoms. Although it is generally benign, malignant variants have been identified.
Ugo Consolo   +3 more
doaj   +1 more source

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