Results 61 to 70 of about 6,352,807 (298)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
, 1968 Copia digital. España : Ministerio de Cultura y Deporte.
Frente Sindicalista Revolucionario de Madrid. Junta Local
core +2 more sources
Assessment for Risk Factors Associated with Local Recurrence in Chordoma [PDF]
, 2015 Background Chordoma is a rare but locally aggressive malignant neoplasm showing notochordal differentiation. The clinical differential diagnoses can be extensive, and definitive diagnosis often relies on histopathologic evaluation.
Abraham, MD, John A. +1 more
core +1 more source
Insights into ImagingObjectives To compare the long-term outcome of radiofrequency ablation (RFA) for local tumor progression (LTP) vs intrahepatic distant recurrence (IDR) in recurrent hepatocellular carcinoma (rHCC), including cases with repeated LTP. Materials and methods
Huan-ling Guo +8 more
doaj +1 more source
Invasive head and neck cutaneous squamous cell carcinoma: clinical and histopathological characteristics, frequency of local recurrence and metastasis [PDF]
Anais Brasileiros de Dermatologia, 2014 BACKGROUND: squamous cell carcinoma is the second most common type of skin malignancy and may evolve to regional lymph node and distant metastases. OBJECTIVE: The objective of this study was to evaluate patients with head and neck cutaneous squamous ...
Luiza Vasconcelos +4 more
doaj +1 more source
Oral and Maxillofacial Surgery Cases, 2022 Solitary fibrous tumor is a rare spindle-cell neoplasm of mesenchymal origin. In head and neck region, the tumors present slow-growing masses, often with local compressive symptoms. Although it is generally benign, malignant variants have been identified.
Ugo Consolo +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Guidelines on parking management : sustainable mobility [PDF]
, 2023 This document is one in a series of documents on Sustainable Mobility and includes other important subjects – Walkability and Accessibility, Shared Transport, Last Mile Transportation and EV Changeover, previously issued by the Local Councils ...
Zammit, Antoine +1 more
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source