Results 51 to 60 of about 3,070,252 (279)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Effects of Long-Term Exposure to News Stereotypes on Implicit and Explicit Attitudes

open access: yesInternational Journal of Communication, 2015
A substantial body of research suggests that some news media outlets depict certain social groups stereotypically. We hypothesize that long-term exposure to such news influences viewers’ automatically activated gut feelings (i.e., implicit attitudes ...
Florian Arendt, Temple Northup
doaj   +2 more sources

Future of the First Amendment: What America's High School Students Think About Their Freedoms [PDF]

open access: yes, 2006
Presents findings from a survey of students and teachers in 34 high schools, that examines attitudes toward First Amendment protections for national and local news media, and student newspapers, and evaluates current education on the rights it ...
David Yalof, Kenneth Dautrich
core  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

72% of Americans Follow Local News Closely [PDF]

open access: yes, 2012
Presents survey findings about characteristics of those who follow local news and information closely, such as connectedness to community, attachment to local newspapers, and topics of interest, as well as differences by age among local news ...

core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Linking Audiences to News: A Network Analysis of Chicago Websites [PDF]

open access: yes, 2011
The mass media model, which sustained news and information in communities like Chicago for decades, is being replaced by a "new news ecosystem" consisting of hundreds of websites, podcasts, video streams and mobile applications.
Rich Gordon, Zachary Johnson
core  

Local Ranking Problem on the BrowseGraph [PDF]

open access: yes, 2015
The "Local Ranking Problem" (LRP) is related to the computation of a centrality-like rank on a local graph, where the scores of the nodes could significantly differ from the ones computed on the global graph.
Andersen R.   +9 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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