Results 71 to 80 of about 3,070,252 (279)

Introverted Locals or World Citizens?

open access: yesNordicom Review, 2009
Claiming that interest in local vs. foreign news is one way of measuring orientation towards local and greater society, this paper utilizes a Norwegian survey with questions about interest in news to identify groups with different orientations. The study
Elvestad Eiri
doaj   +1 more source

EMERGING DIGITAL ECOSYSTEMS [PDF]

open access: yesSocial Sciences and Education Research Review
The digital era has profoundly disrupted traditional local news outlets, leading to widespread closures, the formation of "news deserts," and concerns about diminished civic engagement and democratic health.
Dan Valeriu VOINEA
doaj   +1 more source

Getting Local: How Nonprofit News Ventures Seek Sustainability [PDF]

open access: yes, 2011
Examines eight nonprofit news ventures' mission, audience, reach, and social impact; revenue generation and diversification; and organizational adaptability, innovation, and resource allocation as critical elements of long-term ...

core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Letter from Julia to Family July 3, 1939

open access: yes, 1939
This letter is mostly just local news from the Pearson\u27s ...
George Fox University Archives
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Missed opportunities for community engagement: An examination of the government-funded Local Journalism Initiative

open access: yesFacts & Frictions
This article examines the Local Journalism Initiative (LJI), initially a $70-million, five-year program of the Canadian government to fund new reporting positions in existing newsrooms across Canada, with the goal of increasing the amount of civic ...
Magda Konieczna, Béatrice Girardin
doaj   +1 more source

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