Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency
Advanced Materials, EarlyView.As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang +12 more
wiley +1 more source
A multiscale topology optimization design framework with data driven surrogate model. [PDF]
Sci RepZhou H, Zhou C.
europepmc +1 more source
Advanced Materials Interfaces, EarlyView.A dual‐modulus silicone release film creates distributed stress concentrations at high‐/low‐modulus boundaries, triggering multi‐site crack initiation and rapid interfacial detachment. The architecture lowers the peak separation force by 97.6%, shortens detachment time, and enables stable continuous projection stereolithography at 720 mm h−1, offering ...
Xiaogang Li +3 more
wiley +1 more source
Hydrodynamic Cavitation in Juice Processing: Linking PME, PPO, and POD Responses to Physicochemical Stability and Quality Retention. [PDF]
MoleculesAlbanese L.
europepmc +1 more source
Additively Manufactured Porous Ceramics as Tunable Dielectrics for Passive Temperature Sensing
Advanced Materials Technologies, EarlyView.Porous ceramic lattices, 3D‐printed from a multicomponent oxide ink, are integrated with LC resonators for passive wireless temperature sensing. By tuning porosity, the dielectric properties and RF response are engineered to produce distinct resonant frequency shifts with temperature. The results establish a structure‐driven approach to customizing the
Sogol Heidarishahrivar +5 more
wiley +1 more source
Leveraging Mechanical Resonances for the Selection of Promising Materials in Complex Phase Spaces
Advanced Materials Technologies, EarlyView.A central challenge in materials science is the design of new functional materials with enhanced performance for targeted applications. This paper demonstrates that “listening” to materials through measuring their mechanical resonances is a rich, and largely untapped, platform for the rapid identification of promising novel compounds and a powerful ...
Christopher A. Mizzi +4 more
wiley +1 more source
Evaluating the Mechanical Properties and Energy Absorption Performance of Fluorite Lattice Structures Inspired by Pomelo Peel. [PDF]
Materials (Basel)Nguyen ND, Huang SC.
europepmc +1 more source
Advanced Manufacturing of Composite‐Based Systems for Energy Applications
Advanced Materials Technologies, EarlyView.Advanced manufacturing enables the integration of polymers, ceramics, metal oxides, and composites into architected microstructures with tailored transport pathways. By coupling material selection, manufacturing strategy, and structural design, multifunctional energy systems can simultaneously improve electrochemical performance, thermal management ...
Sri Vaishnavi Thummalapalli +13 more
wiley +1 more source
Multiscale Prediction of Heat and Mass Transport Properties in Cement-Based Materials Based on Hydration Microstructure Evolution. [PDF]
Materials (Basel)Huang F +6 more
europepmc +1 more source
Wood‐Derived Nanocellulose‐Biocarbon Fresnel‐Zone Plate Lenses for Sub‐THz Frequency Applications
Advanced Materials Technologies, EarlyView.Wood‐derived nanocellulose and lignin‐based biocarbon were combined to fabricate fully bio‐based Fresnel zone plate (FZP) lenses for sub‐terahertz frequencies. These sustainable FZP lenses exhibit low dielectric loss and high directivity, achieving performance comparable to that of metallic references, and remain functional under environmental stress ...
Riikka Haataja +9 more
wiley +1 more source