Results 31 to 40 of about 8,952,981 (345)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Women as mayors: the political representation of women in the leadership of Slovak municipalities after the municipal elections in the year 2010 [PDF]

open access: yesAnnales Scientia Politica, 2018
The paper analyses women’s representation at the local level in Slovakia, or at the level of all (almost three thousand) Slovak municipalities, respectively.
Pave Maškarinec
doaj  

An AFSCME Local Transforms Local Politics [PDF]

open access: yes, 1994
[Excerpt] In the late 1980s, AFSCME Local 2703, in Merced, California, found itself in a position familiar to many union members at that time: fighting hard to keep pay and benefits from being slashed.
McLeod, Sean P.
core   +1 more source

The national and local politics of climate change adaptation in Zimbabwe

open access: yes, 2015
The description and analysis of climate change adaptation programmes in low- and middle-income countries rarely examines the political conditions and contexts in which these take place, or the way in which these activities may themselves shape local and ...
D. Dodman, D. Mitlin
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Mimicry or meltdown? On the greening of local new politics parties [PDF]

open access: yes, 2011
By scrutinizing a specific type of local lists - interpreted as a local variant of ‘New Politics Parties’ - this paper aims to give an initial impetus to understanding the internal variations concealed by the all-purpose denominator of local lists. Local
Heyerick, An, Steyvers, Kristof
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Local climate policies in Germany. Challenges of governance and knowledge

open access: yesCogent Social Sciences, 2018
Measures and strategies for climate adaptation and mitigation on the local level have become more or less obligatory. However, local governments face epistemic and organisational uncertainties.
Karsten Zimmermann
doaj   +1 more source

Historicizing the Emergence of Global Mental Health in Nepal (1950-2019) [PDF]

open access: yes, 2020
This article traces a genealogy of mental health governance in Nepal as it was constituted in and through an assemblage of historical events, local politics, personal relationships and trends in the field of global health development.
Seale-Feldman, Aidan
core   +3 more sources

Local values in local political culture and democracy; A review of hermeneutics among local elites [PDF]

open access: yes, 2023
The reforms provided space for local elites, both traditionally based (Bangsawan) and political elites (Bureaucrats-Politicians) to contest in the arena of local democracy.
Arifin, Syamsul   +3 more
core   +1 more source

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