Results 101 to 110 of about 3,043,667 (314)

Developing a Learning Package Covering a Topic on Cells and Tissues Based on Guided-Inquiry Model and Integration of Local Knowledge

open access: yesJurnal Pendidikan Sains, 2017
: This study aims to develop a learning package covering a topic on cells and tissues on the basis of guided-inquiry learning model and integration of local knowledge. The package manifests in a syllabus, lesson plans, and a module.
Kiki Taurista   +2 more
doaj   +1 more source

Can local finance add value to local small business? Evidence from a UK local loan and grant fund [PDF]

open access: yes, 2020
Access to finance is a key constraint on the creation, survival, and growth of SMEs, and this issue has prompted governments to directly intervene in financial markets, but has also led to the development of new forms of financial intermediation and new ...
Baranova, Polina   +3 more
core  

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Science learning module based on local potential of Grenden village on digestive system material to improve problem solving ability of junior high school students

open access: yesJPBI (Jurnal Pendidikan Biologi Indonesia)
Problem-solving ability is a fundamental skill that students must develop in science education. However, many students continue to face challenges in mastering this competence.
Sri Wahyuni   +3 more
doaj   +1 more source

LTAP Technology Exchange (June 2017, vol. 25, no. 2) [PDF]

open access: yes, 2017
Articles include: Countermeasures improve pedestrian safety; Should you use recycled materials to melt ice and snow on your roads?; A primer: calcium chloride for stabilizing gravel roads; Congratulations to the 2016 graduates of the Minnesota LTAP Roads
Minnesota Local Technical Assistance Program
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Anti-immigrant parties, local presence and electoral success [PDF]

open access: yes, 2012
Does the local organisational presence of anti-immigrant parties affect their chances for electoral success? In order to answer this question, the article explores the potential of a supply-oriented explanation to anti-immigrant party success by ...
Loxbo, Karl,   +2 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Local Minimizers in micromagnetics and related problems [PDF]

open access: yes, 2002
Let $\Omega \subset{\bf R}^3$ be a smooth bounded domain and consider the energy functional ${\mathcal J}_{\varepsilon} (m; \Omega) := \int_{\Omega} \left ( \frac{1}{2 \varepsilon} |Dm|^2 + \psi(m) + \frac{1}{2} |h-m|^2 \right) dx + \frac{1}{2} \int_ ...
J M Ball (16079657)   +12 more
core   +2 more sources

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

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