Results 131 to 140 of about 3,043,667 (314)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
The Financial Entanglements of Local Energy Projects [PDF]
, 2015 There is currently an expansion of local energy initiatives, underpinned by the desire to reduce energy-related carbon emissions and in recognition of the importance of the local arena to achieving such change.
Rydin, YJ
core
Local potentials for achieving sustainable development goals: qualitative evidence from local governments in Türkiye [PDF]
Although academia occasionally emphasises prioritising the local dimension in achieving the Sustainable Development Goals (SDGs), the potential of local governments to contribute to SDGs accomplishment remains a relatively unexplored area within academic
Gocoglu, Volkan, Gocoglu, Ipek Didem
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Jurnal PaedagogyThis study aims to develop biology teaching materials based on the local potential of rice farming in Karawang district to enhance students' environmental literacy and problem-solving skills. This study employed a research and development model using the
Cindy Rantika Devi +2 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Developing of environmental education textbook based on local potencies
JPBI (Jurnal Pendidikan Biologi Indonesia), 2017 Environmental education subject aims to form students who have the character to maintain the environment. One effort to achieve the objectives of the Environmental education subject is the local Environmental Education Textbook Based on Local Potencies ...
Silfia Ilma, Fitri Wijarini
doaj
BiosferThis research stems from the low utilization of local potential-based biology learning resources in schools, despite their importance in deepening biological understanding, shaping student character, and fostering environmental awareness, amid growing ...
Hery Fajeriadi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source