Results 91 to 100 of about 5,442,599 (254)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Latin America’s Transformative New Extraction and Local Conflicts

open access: yesEuropean Review of Latin American and Caribbean Studies, 2015
Subterranean Struggles: New Dynamics of Mining, Oil, and Gas in Latin America, edited by Anthony Bebbington and Jeffrey Bury. University of Texas Press, 2013.Unearthing conflict: Corporate Mining, Activism, and Expertise in Peru, by Fabiana Li.
Barbara Hogenboom
doaj   +1 more source

Ab-initio Phonon Calculations for the layered compound TiOCl

open access: yes, 2005
We present first-principles frozen-phonon calculations for the three Raman-active $A_g$ modes in the spin-1/2 layered TiOCl system within two different well-known approaches: the local density approximation (LDA) and the so-called LDA+U approximation. We
Pisani, Leonardo, Valenti, Roser
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew   +11 more
wiley   +1 more source

Newspapers Turning Ideas into Dollars: Four Revenue Success Stories [PDF]

open access: yes, 2013
The report follows a year-long effort to identify newspaper successes in the search for new business models. This report analyzes four such dailies -- the Naples (Fla.) Daily News, the Santa Rosa (Calif.) Press Democrat, the (Salt Lake City) Deseret News,
Amy Mitchell, Mark Jurkowitz
core  

Energetic Components of Cooperative Protein Folding

open access: yes, 2000
A new lattice protein model with a four-helix bundle ground state is analyzed by a parameter-space Monte Carlo histogram technique to evaluate the effects of an extensive variety of model potentials on folding thermodynamics.
A. Kolinski   +40 more
core   +2 more sources

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel   +5 more
wiley   +1 more source

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