Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall +16 more
wiley +1 more source
Local production of medicines in Mozambique: at crossroads of pharmaceutical knowledge circulation
Revue Francophone sur la Santé et les Territoires, 2019 Alila Brossard Antonielli
doaj +1 more source
Local production of lactate, ribose phosphate, and amino acids within human triple-negative breast cancer. [PDF]
Med, 2021 Ghergurovich JM +18 more
europepmc +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Cooking wares from Tropaeum Traiani
Materiale și Cercetări ArheologiceIn this article, we continue the presentation of the archaeological materials discovered at Tropaeum Traiani, in Sector A (north of Basilica A), from 2005 to 2016, with kitchen wares.
Grigoraș, B, Panaite, A.
doaj +1 more source
Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Armed to the Hilt: Nigeria's Battle with Illicit Gun and Local Production in a State of Fragility [PDF]
Košická bezpečnostná revueNigeria is now battling the spread of illegal weapons, which is stoking a number of security concerns that jeopardise its national sovereignty. The Nigerian firearms legislation is essentially unenforceable due to its ineffectiveness and numerous ...
Olagoke Oluwafemi AWOTAYO +3 more
doaj
Towards equity in health: for an agenda for research and development and local production driven by the multiple needs of the Brazilian Unified National Health System. [PDF]
Cad Saude Publica, 2023 Barbeitas MM +3 more
europepmc +1 more source
Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
wiley +1 more source