Results 141 to 150 of about 975,796 (310)

Lipoic Acid‐Intervened Decellularized Stem Cell Spheroid‐Based Injectable Granular Gel for Diabetic Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
ABSTRACT Advancements in tissue engineering have revolutionized therapeutic paradigms for diabetic tissue defects; however, the lack of applicable scaffold containing various bioactive substance aggregates remained a critical bottleneck hindering satisfactory repair effect.
Tao Wang   +8 more
wiley   +1 more source

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

open access: yesAdvanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang   +3 more
wiley   +1 more source

The Effectiveness of Local Taxes on Local Revenue of Bojonegoro Regency

open access: yesJURNAL MANAJEMEN KEUANGAN PUBLIK
This study aims to examine the effectiveness of local taxes in Bojonegoro Regency in increasing local revenue. The data shows that the effectiveness of local taxes consistently exceeds 100%, indicating a very high level of effectiveness. The growth of local tax realization in real terms also shows a positive trend.
Ringga Ananta Putra, Denny Iswanto
openaire   +1 more source

Multifunctional Bioactive Scaffold Facilitating BMSCs‐Driven Osteogenesis and Vascularization in Critical‐Sized Bone Defect Repair

open access: yesAdvanced Science, EarlyView.
A dual‐network bFGF@CB‐gel integrates: i) ChSMA scaffold (mechanical support/BMSCs delivery); ii) BC carrier (sustained bFGF release via EGFL/Itga2b and COMP/PI3K/AKT for adhesion/osteogenesis); iii) bFGF/PI3K/AKT/eNOS for angiogenesis. This rational, synergistic design addresses CSD bone regeneration challenges.
Yunze Feng   +12 more
wiley   +1 more source

A Modular and Programmable Cas13d Platform for RNA Single Nucleotide Variant Detection

open access: yesAdvanced Science, EarlyView.
A scenario‐guided Cas13d platform enables configurable single nucleotide variant ribonucleic acid diagnostics through rule‐based guide design and ribonucleic acid binding domain engineering, supporting amplification‐free ultrasensitive detection and amplification‐coupled robust detection for accurate mutation classification in clinical tumor specimens.
Zeyu Wang   +8 more
wiley   +1 more source

Fiscal federalism in big developing countries: China and India [PDF]

open access: yes
In South and East Asian countries a highly centralized government prevails, although recently some trends are moving toward a greater degree of decentralization.
Fraschini, Angela
core  

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

open access: yesAdvanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan   +24 more
wiley   +1 more source

Intergovernmental fiscal relations in China [PDF]

open access: yes
The choice of the"right"fiscal relationship between central, provincial, and local governments depends on how a government weighs the benefits of decentralized economic development policies against the costs of having less effective central fiscal ...
Bahl, Roy W., Wallich, Christine
core  

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

open access: yesAdvanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng   +8 more
wiley   +1 more source

Determinants of local government revenue and economic potential: Pathways for revenue enchancement

open access: yesOptimum: Jurnal Ekonomi dan Pembangunan
Fiscal independence represents a critical indicator of regional governments' capacity to finance development without dependence on central government transfers. Klaten Regency continues to exhibit low fiscal autonomy levels with suboptimal of local government revenue (LGR) contributions. This study aims to: a).
Rahmawati Riantisari   +2 more
openaire   +1 more source

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