Results 11 to 20 of about 646 (125)
Adeno-associated virus type 5 infection via PDGFRα is associated with Interstitial lung disease in systemic sclerosis and generates composite peptides and epitopes recognized by the agonistic immunoglobulins present in patients with systemic sclerosis [PDF]
Arthritis &Rheumatology, Volume 76, Issue 4, Page 620-630, April 2024., 2023 Objectives: The etiopathogenesis of systemic sclerosis (SSc) is unknown. Platelet-derived growth factor receptors (PDGFRs) are overexpressed in SSc patients.Agarbati, Silvia, Alizzi, Silvia, Amico, Donatella, Amoresano, Angela, Amoroso, Antonio, Avvedimento, Enrico V, Benfaremo, Devis, Chen, Qingxin, Cuccioloni, Massimiliano, Dorfmuller, Peter, Finke, Doreen, Funaro, Ada, Gabrielli, Armando, Galgani, Mario, Gasparini, Stefano, Giordano, Antonio, Grieco, Antonella, Kleinschmidt, Juergen, La Cava, Antonio, Menzo, Stefano, Moroncini, Gianluca, Mozzicafreddo, Matteo, Müller, Martin, Nieto, Karen, Paolini, Chiara, Pezone, Antonio, Pinto, Gabriella, Pucci, Piero, Senzacqua, Martina, Spadoni, Tatiana, Svegliati, Silvia, Tonnini, Cecilia, Viola, Nadia, Zuccatosta, Lina +33 morecore +3 more sourcesBlockade of TGF-β 1 Signalling Inhibits Cardiac NADPH Oxidase Overactivity in Hypertensive Rats [PDF]
Oxidative Medicine and Cellular Longevity, Volume 2012, Issue 1, 2012., 2012 NADPH oxidases constitute a major source of superoxide anion (·O2 −) in hypertension. Several studies suggest an important role of NADPH oxidases in different effects mediated by TGF-β 1.Baltanás, Ana, Borrás-Cuesta, Francisco, Cebrián, Carolina, Dotor, Javier, Díez, Javier, Fortuño, Ana, González, Arantxa, Hermida, Nerea, López, Begoña, Miguel-Carrasco, José Luis, Moreno, María U., Zalba, Guillermo +11 morecore +4 more sourcesFirst-line diagnostic tests to intercept primary heart involvement in systemic sclerosis: Clinical associations from the SPRING-SIR registry. [PDF]
Eur J Clin InvestPrimary heart involvement (pHI) is a severe but often overlooked complication of systemic sclerosis (SSc), linked to heart failure, arrhythmias and mortality. In a study of 600 patients from the Italian SPRING‐SIR registry, 25% had ECG or echocardiographic signs of pHI at baseline, associated with older age, diffuse skin disease and intestinal symptoms.Tonutti A, Motta F, De Angelis R, Cipolletta E, Ferri C, Bajocchi G, Bellando-Randone S, Bruni C, Orlandi M, Zanframundo G, Foti R, Cuomo G, Ariani A, Rosato E, Lepri G, Girelli F, Zanatta E, Bosello SL, Cavazzana I, Ingegnoli F, Cacciapaglia F, Murdaca G, Abignano G, Pettiti G, Rossa AD, Caminiti M, Iuliano AM, Ciano G, Beretta L, Bagnato G, Lubrano E, De Andres I, Idolazzi L, Saracco M, Agnes C, Campochiaro C, Fornaro M, Lumetti F, Spinella A, Magnani L, De Luca G, Codullo V, Visalli E, Iandoli C, Gigante A, Pellegrino G, Pigatto E, Lazzaroni MG, De Lorenzis E, Mennillo G, Di Battista M, Pagano-Mariano G, Furini F, Vultaggio L, Parisi S, Peroni CL, Bianchi G, Fusaro E, Sebastiani GD, Govoni M, D'Angelo S, Cozzi F, Franceschini F, Guiducci S, Dagna L, Doria A, Giuggioli D, Riccieri V, Salvarani C, Iannone F, Matucci-Cerinic M, Selmi C, De Santis M, SPRING‐SIR (Systemic Sclerosis PRogression INvestiGation group of the Italian Society for Rheumatology). +73 moreeuropepmc +2 more sourcesRelapsing polychondritis [PDF]
, 1998 PURPOSE: This article describes a clinically-diagnosed case of relapsing polychondritis (RP), attended at the Hospital São Paulo, and presents a literature review of the subject.Andrade Junior, Ary de, Atallah, Álvaro Nagib, Bueno, Carlos Eduardo, Miyasaka, Lincoln Sakiara +3 morecore +2 more sourcesNintedanib for systemic sclerosis–associated interstitial lung disease [PDF]
, 2019 BackgroundInterstitial lung disease (ILD) is a common manifestation of systemic sclerosis and a leading cause of systemic sclerosis-related death. Nintedanib, a tyrosine kinase inhibitor, has been shown to have antifibrotic and antiinflammatory effects ...Alves, Margarida, Azuma, Arata, Clerisme-Beaty, Emmanuelle, Distler, Oliver, Fischer, Aryeh, Gahlemann, Martina, Girard, Mannaig, Highland, Kristin B., Kuwana, Masataka, Maher, Toby M., Mayes, Maureen D., Raghu, Ganesh, Sauter, Wiebke, SENSCIS Trial Investigator, for the, Smith, Vanessa, Stowasser, Susanne, Tetzlaff, Kay +16 morecore +3 more sourcesGallbladder adenocarcinoma: evaluation of the prognostic factors in 100 resectable cases in Brazil [PDF]
, 2012 BACKGROUND: In spite its relative rarity, gallbladder adenocarcinoma is a neoplasm who presents an aggressive biologic behavior. The single curative treatment has been radical surgical resection with free margin.Artigiani Neto, Ricardo, Farah, José Francisco De Matos, Franco, Maria Isete Fares, Goldenberg, Alberto, Martins, Sandro José, Pais-costa, Sergio Renato +5 morecore +3 more sourcesAtypical hemolytic uremic syndrome [PDF]
, 2011 Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia, thrombocytopenia and renal impairment. Atypical HUS (aHUS) defines non Shiga-toxin-HUS and even if some authors include secondary aHUS due to Streptococcus pneumoniae Chantal Loirat, Véronique Frémeaux-Bacchi +1 morecore +2 more sourcesThe multifaceted roles of perlecan in fibrosis [PDF]
, 2018 Perlecan, or heparan sulfate proteoglycan 2 (HSPG2), is a ubiquitous heparan sulfate proteoglycan that has major roles in tissue and organ development and wound healing by orchestrating the binding and signaling of mitogens and morphogens to cells in a ...Al-Ahmad, Andersson-Sjoland, Andersson-Sjoland, Arthur, Ashikari-Hada, Asplund, Aviezer, Barkefors, Barros, Behrens, Beller, Bengtsson, Bingley, Bishop, Bittencourt, Bix, Bix, Borkham-Kamphorst, Bremnes, Burgess, Cailhier, Cassiman, Celie, Ceol, Chakravarti, Chen, Chilosi, Chuang, Chuang, Cohen, Conde-Knape, Conte, Costell, Di Sario, Dos Santos, Duffield, Ebefors, Edgar, Esko, Evanko, Farach-Carson, Farach-Carson, Fengying Tang, Fernandez, Forsberg, Friedman, Friedman, Fujii, Gallai, Garl, Ge, Gellersen, Giros, Gohring, Gonzalez, Gonzalez, Goyal, Gressner, Gubbiotti, Guo, Hajari Case, Hallgren, Hammond, Hashimoto, Haubst, Hayashi, Hayward, Hedin, Hedin, Hering, Hilberg, Hisatomi, Ichimaru, Ikeguchi, Iozzo, Iozzo, Iozzo, Iredale, James G.W. Smith, James Melrose, Jelena Rnjak-Kovacina, John M. Whitelock, Jung, Kahari, Kaji, Kennett, Kinsella, Knox, Knox, Knox, Knox, Kotaru, Kovalszky, Koyama, Krimmer, Kunjathoor, Kvist, Laplante, Laplante, Leask, Leask, Leask, Lee, Lee, Lee, Lekkerkerker, Levy, Liang, Lord, Lord, Lord, Lord, Lundkvist, Mak, Mak, Mak, Malmstrom, Marra, Martinez-Hernandez, Martinez-Hernandez, Marx, Marzoll, Masola, Matsui, Matsuo, Megan S. Lord, Melrose, Melrose, Menzel, Mitra, Mollmark, Mongiat, Mongiat, Moon, Murphy, Musso, Nagy, Nakamura, Nakayama, Narita, Nguyen, Nihlberg, Nilsson, Ogawa, Ohkawara, Ozaki, Paka, Patel, Pillarisetti, Pinzani, Poluri, Pozzi, Raines, Raj, Rauch, Raymond, Rees, Rienstra, Rnjak-Kovacina, Rojkind, Rolls, Rosenzweig, Roskams, Ross, Sahin, Sakai, Salem, Sato, Schaefer, Schafer, Segev, Sharma, Shimizu-Hirota, Singh, Sofroniew, Sweeney, Tang, Tang, Tannock, Tao, Teh, Teimouri, Theret, Thomas, Thyberg, Timpl, Tomasek, Tran, Tran, Tran-Lundmark, Tátrai, Uchimura, Vanheule, Venkatesan, Venkatesan, Wang, Weiser, Weiser, Westergren-Thorsson, Westergren-Thorsson, Westergren-Thorsson, Whitelock, Whitelock, Whitelock, Whitelock, Willis, Wollin, Wollin, Woodall, Xu, Yamamoto, Yang, Yaoi, Yue, Yung, Yung, Zeisberg, Zeisberg +217 morecore +1 more sourceBilayered, non‐cross‐linked collagen matrix for regeneration of facial defects after skin cancer removal: a new perspective for biomaterial‐based tissue reconstruction
Journal of Cell Communication and Signaling, Volume 10, Issue 1, Page 3-15, March 2016., 2016 Abstract
Classically skin defects are covered by split thickness skin grafts or by means of local or regional skin flaps. In the presented case series for the first time a bilayered, non‐crossed‐linked collagen matrix has been used in an off‐label fashion in order to reconstruct facial skin defects following different types of skin cancer resection ...Shahram Ghanaati, Adorján Kovács, Mike Barbeck, Jonas Lorenz, Anna Teiler, Nader Sadeghi, Charles James Kirkpatrick, Robert Sader +7 morewiley +1 more source
