Results 41 to 50 of about 12,744,146 (299)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Phosphorus recovery potential from sewage sludge by struvite precipitation: remodelling policy framework in Rajasthan, India

Water Science and Technology
The manufacturing of fossil-based fertilizers by extraction of rock phosphate has contributed to carbon emissions and depleted the non-renewable phosphorus reserves.
Ankit Srivastava, Kanika Saxena, Urmila Brighu   +2 more
doaj   +1 more source

The Term "Local Authority" in the European Charter of Local-Self Government: Different Meanings Lead to Different Implementation

University of Bologna Law Review, 2018
The article takes a critical look at the meaning of the term “local authority”which is one of the main terms of the European Charter of Local-Self Government and considers the question: “can the meaning of the term “local authority” change theessence of ...
Sergiy Panasyuk
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Designing Local Self-government Evaluation Model in Provincial Level in Islamic Republic of Iran [PDF]

مدیریت دولتی, 2018
Objective: The de-concentrated organizing of provinces along with the expanse of country, ethnic and religious diversity and the massive volume of public services, have confronted Islamic Republic of Iran with various problemssuch as reducing ...
zahir Alimorai, Abdolhamid Shams, Ali Jahangiri   +2 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Problematic issues of the legal regulation of local self-government officials’ remuneration

Bulletin of Kharkiv National University of Internal Affairs
The article draws attention to the fact that the current legislation on local self-government and service in local self-government bodies contains a number of problematic issues in terms of regulation of remuneration of officials.
V. S. Govorov
doaj   +1 more source

Formation and development of local self-government agencies in Ukraine (1991–2019)

Law and Safety, 2020
Local self-government is an integral part of a democratic society, since it actively influ-ences the political and socio-economic conditions for the development of civil society, and becomes an important prerequisite for the creation of a democratic and ...
Yu. O. Zahumenna, V. V. Lazarev
doaj   +1 more source

An Investigation of the Consequences of Local Self-Governance in the Provinces of the Islamic Republic of Iran [PDF]

دولت‌پژوهی, 2019
The decentralized organization pattern of the Islamic Republic of Iran provinces, along with a variety of public services and climatic, ethnic, cultural and religious differences, have made the country encounter a number of problems.
Zahir Alimoradi
doaj   +1 more source