Results 101 to 110 of about 11,197,720 (252)
PLoS ONEIntroductionExercise produces an immediate lessening of pain sensitivity (Exercise-Induced Hypoalgesia (EIH)) in healthy individuals at local and distant sites, possibly through a shared mechanism with conditioned pain modulation (CPM).
Abigail T Wilson +3 more
doaj +1 more source
Publicly Funded Cleanups Site Status Report 1998: Site Highlights
, 1998 This section includes site highlights from the Publicly Funded Cleanups Site Status Report 1998. Superfund and non-superfund sites are mentioned.This document is available in a total of 27 parts, linked through the related documents field at the end of ...
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Big Local Partnership Member Surveys, 2016-2024
copyright UK Data Service and data collection copyright owner.Big Local is a long-term, place-based funding programme in England aimed at empowering residents in selected communities to lead local change, build community capacity, and improve outcomes ...
Local Trust
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Le choix de nos projets de recherche doit-il dépendre des possibilités d’accès aux terrains, de la disponibilité des données, des angles morts à combler dans le champ de la connaissance, ou encore, de l’ensemble des connections et des affects qui ...
Off-Site
core +1 more source
EPR, Robustness and the Causal Markov Condition [PDF]
, 2007 It is still a matter of controversy whether the Principle of the Common Cause (PCC) can be used as a basis for sound causal inference. It is thus to be expected that its application to quantum mechanics should be a correspondingly controversial issue ...
San Pedro, Iñaki, Suárez, Mauricio
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Site-specific local polarisation curve measurements for probing localised corrosion and inhibition
, 2023 Site-specific local polarisation curve measurements for probing localised corrosion and ...
Medhani Pathirana (13226376) +2 more
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